SCHEMBL6138419

SCHEMBL6138419

Nc1cccc(C2c3ccccc3-c3ccccc32)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.44
CASP1 P29466 1/20 0.44
RECQL P46063 1/20 0.44
CDK5 Q00535 2/20 0.41
MAP4K4 O95819 2/20 0.41
CHEK1 O14757 1/20 0.41
AURKA O14965 1/20 0.41
DAPK3 O43293 1/20 0.41
JAK2 O60674 1/20 0.41
PRKD3 O94806 1/20 0.41
PAK4 O96013 1/20 0.41
ABL1 P00519 1/20 0.41
NTRK1 P04629 1/20 0.41
LCK P06239 1/20 0.41
FYN P06241 1/20 0.41
CSF1R P07333 1/20 0.41
RET P07949 1/20 0.41
IGF1R P08069 1/20 0.41
MET P08581 1/20 0.41
PDGFRB P09619 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13576598 0.89 CYP3A4 (0.50) CYP3A4CASP1RECQLCDK5MAP4K4
SCHEMBL28851605 0.87 HTR2A (0.44) CYP3A4HTR2AALDH1A1L3MBTL1CA1
SCHEMBL16158397 0.84 CDK5 (0.50) CYP3A4CASP1RECQLCDK5MAP4K4
SCHEMBL7805128 0.83 HTR2A (0.41) CYP3A4CASP1RECQLCDK5MAP4K4
SCHEMBL29601950 0.80 CDK5 (0.54) CYP3A4CDK5MAP4K4CHEK1AURKA
SCHEMBL2098554 0.79 MAOA (0.44) CYP3A4CASP1RECQLCDK5MAP4K4
SCHEMBL18481976 0.78 HTR2A (0.38) CYP3A4HTR2AALDH1A1L3MBTL1CA1
SCHEMBL28038360 0.78 HTR2A (0.38) CYP3A4HTR2AALDH1A1L3MBTL1LMNA
SCHEMBL28946044 0.78 CYP19A1 (0.43) HTR2AALDH1A1MEN1KMT2ANPC1
SCHEMBL19303899 0.78 MEN1 (0.49) HTR2AALDH1A1TDP1MEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113150545-B Polymer film containing nano fullerene and preparation method thereof 北京市科学技术研究院分析测试研究所(北京市理化分析测试中心) 2022-11-15 CN claimed
CN-117120516-A Polyimide, resin composition, polyimide film, and method for producing same 旭化成株式会社 2023-11-24 CN disclosed
CN-116554473-A Thermoplastic polyimide and application thereof in temporary bonding technology 深圳先进电子材料国际创新研究院 2023-08-08 CN disclosed
CN-114683633-A Laminate and method for manufacturing same 律胜科技股份有限公司 2022-07-01 CN disclosed
EP-1117102-B1 Method of manufacturing material for forming insulating film JSR CORP (JP) 2005-08-10 EP disclosed
EP-1117102-A2 Method of manufacturing material for forming insulating film JSR Corporation (JP) 2001-07-18 EP disclosed