Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK5 | Q00535 | 2/20 | 0.54 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.54 |
| ▸ | AURKA | O14965 | 1/20 | 0.54 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.54 |
| ▸ | JAK2 | O60674 | 1/20 | 0.54 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.54 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.54 |
| ▸ | PAK4 | O96013 | 1/20 | 0.54 |
| ▸ | ABL1 | P00519 | 1/20 | 0.54 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.54 |
| ▸ | LCK | P06239 | 1/20 | 0.54 |
| ▸ | FYN | P06241 | 1/20 | 0.54 |
| ▸ | CSF1R | P07333 | 1/20 | 0.54 |
| ▸ | RET | P07949 | 1/20 | 0.54 |
| ▸ | IGF1R | P08069 | 1/20 | 0.54 |
| ▸ | MET | P08581 | 1/20 | 0.54 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.54 |
| ▸ | PIM1 | P11309 | 1/20 | 0.54 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.54 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16158397 | 0.89 | CDK5 (0.50) | CDK5CHEK1AURKADAPK3JAK2 | |
| SCHEMBL70993 | 0.83 | LMNA (0.54) | CDK5CHEK1AURKADAPK3JAK2 | |
| Benzene SCHEMBL27791155 | 0.83 | LMNA (0.54) | CDK5CHEK1AURKADAPK3JAK2 | |
| SCHEMBL29370508 | 0.83 | LMNA (0.54) | CDK5CHEK1AURKADAPK3JAK2 | |
| SCHEMBL25171318 | 0.83 | LMNA (0.54) | CDK5CHEK1AURKADAPK3JAK2 | |
| SCHEMBL1681655 | 0.81 | HTR2A (0.43) | CDK5CHEK1AURKADAPK3JAK2 | |
| SCHEMBL6138419 | 0.80 | CYP3A4 (0.44) | CDK5CHEK1AURKADAPK3JAK2 | |
| SCHEMBL20869346 | 0.79 | MEN1 (0.43) | CDK5CHEK1AURKADAPK3JAK2 | |
| SCHEMBL21174548 | 0.79 | MEN1 (0.43) | CDK5CHEK1AURKADAPK3JAK2 | |
| SCHEMBL22068817 | 0.79 | GAA (0.49) | CDK5CHEK1AURKADAPK3JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12069950-B2 | Materials for electronic devices | MERCK KGAA (DE) | 2024-08-20 | — | — | US | disclosed |
| US-20220158101-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2022-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12069950-B2 | Materials for electronic devices | EED, EPHA6, ERCC1 | CDK5 2291/4885CHEK1 1768/4885AURKA 3243/4885 |
| US-20220158101-A1 | MATERIALS FOR ELECTRONIC DEVICES | EED, EPHA6, ERCC1 | CDK5 2291/4885CHEK1 1768/4885AURKA 3243/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.