SCHEMBL1615985

SCHEMBL1615985

O=C1COC(=O)c2ccccc2O1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.52
MAOA P21397 1/20 0.52
PKM P14618 1/20 0.45
TSHR P16473 1/20 0.45
ALOX15 P16050 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
KDM4E B2RXH2 3/20 0.40
ALDH1A1 P00352 2/20 0.40
TYMS P04818 2/20 0.40
CYP1A2 P05177 1/20 0.40
HPGD P15428 1/20 0.40
CYP2C19 P33261 1/20 0.40
HSD17B10 Q99714 1/20 0.40
STK17B O94768 1/20 0.38
CYP19A1 P11511 1/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
MCL1 Q07820 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14447058 0.84 PKM (0.42) MAOBMAOAPKMTSHRALOX15
SCHEMBL279547 0.80 ABCG2 (0.46) MAOBMAOAPKMTSHRSMN1; SMN2
SCHEMBL29966720 0.80 ABCG2 (0.46) MAOBMAOAPKMTSHRSMN1; SMN2
SCHEMBL5940959 0.80 MAOB (0.64) MAOBMAOAPKMTSHRTDP1
SCHEMBL19754922 0.74 TDP1 (0.63) MAOBMAOAPKMTSHRALOX15
SCHEMBL167093 0.74
SCHEMBL12691224 0.74 TDP1 (0.63) MAOBMAOAPKMTSHRALOX15
SCHEMBL30320031 0.74 TDP1 (0.63) MAOBMAOAPKMTSHRALOX15
SCHEMBL2604370 0.72 MAOB (0.43) MAOBMAOAPKMTSHRALOX15
SCHEMBL29366641 0.72 MAOB (0.43) MAOBMAOAPKMTSHRALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7923528-B2 Homopolymer or copolymer with glycolide, (L)-lactide, an alkylene carbonate, p-dioxanone, epsilon -caprolactone, 1,4-dioxepan-2-one, or 1,5-dioxepan-2-one; degradation releases salicylic acid BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2011-04-12 US disclosed
US-7923528-B2 Homopolymer or copolymer with glycolide, (L)-lactide, an alkylene carbonate, p-dioxanone, epsilon -caprolactone, 1,4-dioxepan-2-one, or 1,5-dioxepan-2-one; degradation releases salicylic acid BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2011-04-12 US disclosed
US-7923528-B2 Homopolymer or copolymer with glycolide, (L)-lactide, an alkylene carbonate, p-dioxanone, epsilon -caprolactone, 1,4-dioxepan-2-one, or 1,5-dioxepan-2-one; degradation releases salicylic acid BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2011-04-12 US disclosed
US-20080146774-A1 Degradable 1,4-benzodioxepin-3-hexyl-2,5-dione monomer derived polymer with a high glass transition temperature BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2008-06-19 US disclosed
US-20080146774-A1 Degradable 1,4-benzodioxepin-3-hexyl-2,5-dione monomer derived polymer with a high glass transition temperature BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2008-06-19 US disclosed
US-20080146774-A1 Degradable 1,4-benzodioxepin-3-hexyl-2,5-dione monomer derived polymer with a high glass transition temperature BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2008-06-19 US disclosed
WO-2008054727-A2 DEGRADABLE 1,4-BENZODIOXEPIN-3-HEXYL-2,5-DIONE MONOMER DERIVED POLYMER WITH A HIGH GLASS TRANSITION TEMPERATURE MICHIGAN STATE UNIVERSITY (US) 2008-05-08 WO disclosed
WO-2008054727-A2 DEGRADABLE 1,4-BENZODIOXEPIN-3-HEXYL-2,5-DIONE MONOMER DERIVED POLYMER WITH A HIGH GLASS TRANSITION TEMPERATURE MICHIGAN STATE UNIVERSITY (US) 2008-05-08 WO disclosed
EP-0471364-A2 Homopolymers and copolymers of cyclic esters of salicylic acid ETHICON, INC. (US) 1992-02-19 EP disclosed
US-5082925-A Surgical devices, polyesters ETHICON, INC. (US) 1992-01-21 US disclosed