SCHEMBL279547

SCHEMBL279547

O=C1COc2ccccc2O1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 1/20 0.46
ITGB2 P05107 1/20 0.46
ICAM1 P05362 1/20 0.46
ITGAL P20701 1/20 0.46
LMNA P02545 3/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
MAOB P27338 3/20 0.41
MAOA P21397 2/20 0.41
CRHBP P24387 2/20 0.41
CRHR2 Q13324 2/20 0.41
HTT P42858 1/20 0.41
TSHR P16473 2/20 0.40
PKM P14618 1/20 0.40
DAPK3 O43293 1/20 0.38
RET P07949 1/20 0.38
PRKACA P17612 1/20 0.38
GRK5 P34947 1/20 0.38
CDK8 P49336 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29966720 1.00 ABCG2 (0.46) ABCG2ITGB2ICAM1ITGALLMNA
SCHEMBL1615985 0.80 MAOB (0.52) ABCG2ITGB2ICAM1ITGALLMNA
SCHEMBL15026854 0.79 DHODH (0.40) SMN1; SMN2NPC1RAB9AMAOBMAOA
SCHEMBL7754901 0.78 SMN1; SMN2 (0.61) ABCG2ITGB2ICAM1ITGALLMNA
SCHEMBL15763902 0.77 MAOA (0.46) ABCG2ITGB2ICAM1ITGALMAOB
SCHEMBL868520 0.77 ABCG2 (0.52) ABCG2ITGB2ICAM1ITGALLMNA
SCHEMBL14447058 0.77 PKM (0.42) SMN1; SMN2MAOBMAOATSHRPKM
SCHEMBL7256530 0.76 MAOA (0.46) LMNASMN1; SMN2NPC1RAB9AMAOB
SCHEMBL31540329 0.76 MAOA (0.46) LMNASMN1; SMN2NPC1RAB9AMAOB
SCHEMBL5045846 0.74 MAOA (0.50) ABCG2ITGB2ICAM1ITGALLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 132 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11987653-B1 Olefin polymerizations and printing methods thereof UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2024-05-21 US claimed
WO-2000061573-A1 NOVEL BENZODIOXINONES AND METHOD FOR OBTAINING SAME RHODIA CHIMIE (FR) 2000-10-19 WO claimed
US-4681955-A INSECTICIDES, MITICIDES, PYROCATECHOLS, CARBONYL COMPOUNDS, CYCLIZATION, HALOGENATION BAYER AKTIENGESELLSCHAFT (DE) 1987-07-21 US claimed
WO-2025202313-A1 METHOD FOR THE SIMULTANEOUS REPLICATION OF A MULTILAYER POLYCHROMATIC HOLOGRAM CARL ZEISS JENA GMBH (DE) 2025-10-02 WO disclosed
CN-120192314-A Aryl heterocycle Kv1.3 inhibitor and preparation method and application thereof 上海深势唯思科技有限责任公司 2025-06-24 CN disclosed
US-11987653-B1 Olefin polymerizations and printing methods thereof UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2024-05-21 US disclosed
CN-117769421-A Combination therapy for treating cancer using PRMT5 inhibitors 米拉蒂医疗股份有限公司 2024-03-26 CN disclosed
CN-117769420-A Combination therapy for treating cancer using PRMT5 inhibitors 米拉蒂医疗股份有限公司 2024-03-26 CN disclosed
CN-117534682-A Monofunctional bio-based benzoxazine monomer with multi-benzodioxole structure and resin 江苏大学 2024-02-09 CN disclosed
EP-3544972-B1 HETEROARYLPHENOXY BENZAMIDE KAPPA OPIOID LIGANDS PFIZER (US) 2023-04-26 EP disclosed
CN-110234638-B Heteroaryl phenoxy benzamide KAPPA opioid ligands 辉瑞大药厂 2022-10-21 CN disclosed
US-4294266-A SMOKING TOBACCO INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1981-10-13 US disclosed
US-4294266-A SMOKING TOBACCO INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1981-10-13 US disclosed
US-4264456-A IN FABRIC SOFTENER INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1981-04-28 US disclosed
US-4264456-A IN FABRIC SOFTENER INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1981-04-28 US disclosed
US-4259214-A PERFUME ADDITIVE INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1981-03-31 US disclosed
US-4259214-A PERFUME ADDITIVE INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1981-03-31 US disclosed
US-4255275-A FOR SOLID OR LIQUID DETERGENTS INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1981-03-10 US disclosed
US-4255275-A FOR SOLID OR LIQUID DETERGENTS INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1981-03-10 US disclosed
US-4241097-A Use of benzodionones in augmenting or enhancing the aroma and taste of a foodstuff INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1980-12-23 US disclosed