Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.68 |
| ▸ | EGFR | P00533 | 2/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.66 |
| ▸ | MEN1 | O00255 | 4/20 | 0.66 |
| ▸ | MAPT | P10636 | 3/20 | 0.66 |
| ▸ | NPC1 | O15118 | 1/20 | 0.66 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | PTP4A1 | Q93096 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.54 |
| ▸ | PTP4A2 | Q12974 | 1/20 | 0.54 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.53 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.53 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | COMT | P21964 | 1/20 | 0.53 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8848401 | 0.88 | FTO (0.69) | ALDH1A1KDM4EEGFRTDP1KMT2A | |
| SCHEMBL16160390 | 0.88 | FTO (0.69) | ALDH1A1KDM4EEGFRTDP1KMT2A | |
| SCHEMBL8848400 | 0.88 | FTO (0.69) | ALDH1A1KDM4EEGFRTDP1KMT2A | |
| SCHEMBL2211505 | 0.87 | ALDH1A1 (0.75) | ALDH1A1KDM4EEGFRTDP1KMT2A | |
| SCHEMBL23530140 | 0.87 | ALDH1A1 (0.75) | ALDH1A1KDM4EEGFRTDP1KMT2A | |
| SCHEMBL22259764 | 0.86 | ALDH1A1 (0.73) | ALDH1A1KDM4ETDP1KMT2AMEN1 | |
| SCHEMBL29813583 | 0.85 | EGFR (0.73) | ALDH1A1KDM4EEGFRTDP1KMT2A | |
| SCHEMBL29813596 | 0.84 | EGFR (0.72) | ALDH1A1KDM4EEGFRTDP1KMT2A | |
| SCHEMBL1405287 | 0.84 | MEN1 (0.77) | ALDH1A1KDM4EEGFRTDP1KMT2A | |
| SCHEMBL1405285 | 0.84 | MEN1 (0.77) | ALDH1A1KDM4EEGFRTDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014164667-A1 | DENGUE AND WEST NILE VIRUS PROTEASE INHIBITORS | GEORGETOWN UNIVERSITY (US) | 2014-10-09 | — | — | WO | disclosed |