SCHEMBL2211505

SCHEMBL2211505

CCOC(=O)C(C#N)=Cc1cc(OC)c(O)c(OC)c1

nearest known ligand 0.75

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 5/20 0.75
▸ MAPT P10636 4/20 0.75
▸ MEN1 O00255 2/20 0.75
▸ KMT2A Q03164 2/20 0.75
▸ PKM P14618 1/20 0.74
▸ HTT P42858 1/20 0.74
▸ PTP4A1 Q93096 3/20 0.70
▸ PTP4A3 O75365 2/20 0.64
▸ PTP4A2 Q12974 2/20 0.64
▸ DNM1 Q05193 5/20 0.58
▸ KDM4E B2RXH2 3/20 0.57
▸ TDP1 Q9NUW8 1/20 0.57
▸ PDCD1 Q15116 1/20 0.56
▸ CD274 Q9NZQ7 1/20 0.56
▸ EGFR P00533 1/20 0.55
▸ MIF P14174 1/20 0.55
▸ HPGD P15428 1/20 0.55
▸ NPSR1 Q6W5P4 1/20 0.55
▸ RXFP1 Q9HBX9 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23530140 1.00 ALDH1A1 (0.75) ALDH1A1MAPTMEN1KMT2APKM
SCHEMBL27446825 0.91 PTP4A1 (0.81) ALDH1A1MAPTMEN1KMT2APKM
SCHEMBL2215142 0.89 ALDH1A1 (0.74) ALDH1A1MAPTMEN1KMT2APKM
SCHEMBL10678680 0.88 ALDH1A1 (0.73) ALDH1A1MAPTMEN1KMT2APKM
SCHEMBL10678676 0.88 ALDH1A1 (0.73) ALDH1A1MAPTMEN1KMT2APKM
SCHEMBL16160385 0.87 ALDH1A1 (0.68) ALDH1A1MAPTMEN1KMT2APKM
SCHEMBL16160400 0.87 ALDH1A1 (0.62) ALDH1A1MAPTMEN1KMT2APKM
SCHEMBL11853030 0.86 ALDH1A1 (0.70) ALDH1A1MAPTMEN1KMT2APKM
SCHEMBL22897308 0.86 ALDH1A1 (1.00) ALDH1A1MAPTMEN1KMT2APKM
SCHEMBL30883296 0.86 ALDH1A1 (1.00) ALDH1A1MAPTMEN1KMT2APKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4076677-A1 COMPOSITION COMPRISING AT LEAST 5% BY WEIGHT OF TITANIUM OXIDES, AN A-CYANODIPHENYLACRYLATE DERIVATIVE AND A 4-HYDROXYBENZYLIDENEMALONATE OR 4-HYDROXYCINNAMATE DERIVATIVE L'OREAL (FR) 2022-10-26 — — EP claimed
US-20100047185-A1 ACTVIE SUBSTANCE COMBINATION ISDIN S.A. (ES) 2010-02-25 — — US claimed
WO-2008083975-A1 LIGHT-STABILIZED COMPOSITION ISDIN S.A. (ES) 2008-07-17 — — WO claimed
WO-2008083974-A1 ACTIVE SUBSTANCE COMBINATION ISDIN S.A. (ES) 2008-07-17 — — WO claimed
WO-2008067928-A1 UV ABSORBING COMPOSITIONS CONTAINING A PYRROLYLTRIAZINE ISDIN S.A. (ES) 2008-06-12 — — WO claimed
US-7150876-B2 Methods for stabilizing ingredients within cosmetics, personal care and household products MERCK PATENT GMBH (DE) 2006-12-19 — — US claimed
US-20050244349-A1 Methods for stabilizing ingredients within cosmetics, personal care and household products SUSONITY Commercial GmbH (DE) 2005-11-03 — — US claimed
US-20030108492-A1 PHOTO STABLE ORGANIC SUNSCREEN COMPOUNDS WITH ANTIOXIDANT PROPERTIES AND COMPOSITIONS OBTAINED THEREFROM EM INDUSTRIES 2003-06-12 — — US claimed
US-20240122828-A1 ALKENONE-BASED FORMULATIONS FOR TOPICAL APPLICATIONS WESTERN WASHINGTON UNIVERSITY 2024-04-18 — — US disclosed
WO-2024003594-A1 PERSONAL CARE COMPOSITIONS COMPRISING PANCRATIUM MARITIMUM Galderma Holding SA (CH) 2024-01-04 — — WO disclosed
US-11839675-B2 Alkenone-based formulations for topical applications WESTERN WASHINGTON UNIVERSITY (US) 2023-12-12 — — US disclosed
WO-2023192538-A1 PERSONAL CARE COMPOSITIONS FOR SENSITIVE SKIN AND METHODS OF USE Galderma Holding SA (CH) 2023-10-05 — — WO disclosed
EP-4076677-A1 COMPOSITION COMPRISING AT LEAST 5% BY WEIGHT OF TITANIUM OXIDES, AN A-CYANODIPHENYLACRYLATE DERIVATIVE AND A 4-HYDROXYBENZYLIDENEMALONATE OR 4-HYDROXYCINNAMATE DERIVATIVE L'OREAL (FR) 2022-10-26 — — EP disclosed
US-20210361546-A1 ALKENONE-BASED FORMULATIONS FOR TOPICAL APPLICATIONS WOODS HOLE OCEANOGRAPHIC INSTITUTION (US) 2021-11-25 — — US disclosed
US-20050244349-A1 Methods for stabilizing ingredients within cosmetics, personal care and household products SUSONITY Commercial GmbH (DE) 2005-11-03 — — US disclosed
US-20040247536-A1 Photo stable organic sunscreen compositions EMD CHEMICALS, INC. 2004-12-09 — — US disclosed
EP-1406582-A1 PHOTOSTABLE ORGANIC SUNSCREEN COMPOUNDS WITH ANTIOXIDANT PROPERTIES AND COMPOSITIONS OBTAINED THEREFROM MERCK PATENT GmbH (DE) 2004-04-14 — — EP disclosed
US-6602515-B2 Alpha-acetyl-3,5-dimethoxy-4-hydroxy cinnamate ester; dipalmitoyl-3,5- dimethoxy-4-hydroxy benzylidene malonate or amide derivatives EM INDUSTRIES 2003-08-05 — — US disclosed
US-20030108492-A1 PHOTO STABLE ORGANIC SUNSCREEN COMPOUNDS WITH ANTIOXIDANT PROPERTIES AND COMPOSITIONS OBTAINED THEREFROM EM INDUSTRIES 2003-06-12 — — US disclosed
WO-2003007906-A1 PHOTOSTABLE ORGANIC SUNSCREEN COMPOUNDS WITH ANTIOXIDANT PROPERTIES AND COMPOSITIONS OBTAINED THEREFROM MERCK PATENT GMBH (DE) 2003-01-30 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11839675-B2 Alkenone-based formulations for topical applications CUTA, LAGE3, KRT18 ALDH1A1 736/4885MAPT 1549/4885MEN1 2930/4885
US-20050244349-A1 Methods for stabilizing ingredients within cosmetics, personal care and household products CUTA, TYR, LAGE3 ALDH1A1 462/4885MAPT 328/4885MEN1 833/4885
US-20210361546-A1 ALKENONE-BASED FORMULATIONS FOR TOPICAL APPLICATIONS CUTA, LAGE3, KRT18 ALDH1A1 736/4885MAPT 1549/4885MEN1 2930/4885
US-20100047185-A1 ACTVIE SUBSTANCE COMBINATION UGT2B17, TACR2, UGT1A1 ALDH1A1 28/4885MAPT 922/4885MEN1 2776/4885
US-20240122828-A1 ALKENONE-BASED FORMULATIONS FOR TOPICAL APPLICATIONS CUTA, LAGE3, DSG1 ALDH1A1 729/4885MAPT 2360/4885MEN1 3323/4885
US-20030108492-A1 PHOTO STABLE ORGANIC SUNSCREEN COMPOUNDS WITH ANTIOXIDANT PROPERTIES AND COMPOSITIONS OBTAINED THEREFROM ERCC1, ERCC4, OGG1 ALDH1A1 71/4885MAPT 1118/4885MEN1 2394/4885
US-20040247536-A1 Photo stable organic sunscreen compositions SUN2, CCNB1, TYR ALDH1A1 1036/4885MAPT 272/4885MEN1 3106/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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