Sugi Predict

Sugi Predict / Compounds / SCHEMBL1616239

SCHEMBL1616239

SCHEMBL1616239

O=Cc1c2ccccc2c(Cl)c2ccccc12

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PADI4 Q9UM07 1/20 0.52
▸ MEN1 O00255 4/20 0.48
▸ KMT2A Q03164 4/20 0.48
▸ ALDH1A1 P00352 3/20 0.48
▸ TDP1 Q9NUW8 3/20 0.48
▸ NPSR1 Q6W5P4 4/20 0.45
▸ MAPT P10636 3/20 0.45
▸ LMNA P02545 3/20 0.45
▸ CYP1A2 P05177 2/20 0.45
▸ BLM P54132 2/20 0.45
▸ SMN1; SMN2 Q16637 2/20 0.45
▸ GMNN O75496 1/20 0.45
▸ TP53 P04637 1/20 0.45
▸ POLB P06746 1/20 0.45
▸ ELANE P08246 1/20 0.45
▸ CTSG P08311 1/20 0.45
▸ CTSA P10619 1/20 0.45
▸ CYP2D6 P10635 1/20 0.45
▸ CYP2C9 P11712 1/20 0.45
▸ ALOX15 P16050 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10515166 0.88 PADI4 (0.50) PADI4MEN1KMT2AALDH1A1TDP1
SCHEMBL29588097 0.87 PADI4 (0.64) PADI4MEN1KMT2AALDH1A1TDP1
SCHEMBL986883 0.87 PADI4 (0.64) PADI4MEN1KMT2AALDH1A1TDP1
SCHEMBL10348681 0.86 ERN1 (0.42) PADI4MEN1KMT2AALDH1A1TDP1
SCHEMBL10488425 0.86 SLC2A1 (0.54) PADI4MEN1KMT2AALDH1A1TDP1
SCHEMBL10488239 0.86 SLC2A1 (0.54) PADI4MEN1KMT2AALDH1A1TDP1
SCHEMBL10488283 0.84 PADI4 (0.40) PADI4MEN1KMT2AALDH1A1TDP1
Hydrochloric Acid SCHEMBL9397561 0.84 PADI4 (0.61) PADI4MEN1KMT2AALDH1A1TDP1
Iodide SCHEMBL9460922 0.84 PADI4 (0.61) PADI4MEN1KMT2AALDH1A1TDP1
Bromide SCHEMBL11303999 0.84 PADI4 (0.61) PADI4MEN1KMT2AALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 155 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104327106-A Preparation method of high-sterically-hindered arylborate compound SHENZHEN RES INST THE HONG KONG POLYTECHNIC UNIVERSITY 2015-02-04 — — CN claimed
US-20040132807-A1 Aurones as telomerase inhibitors PHARMACIA ITALIA SPA (IT) 2004-07-08 — — US claimed
EP-1381359-A1 AURONES AS TELOMERASE INHIBITORS Pharmacia Italia S.p.A. (IT) 2004-01-21 — — EP claimed
WO-2002083123-A1 AURONES AS TELOMERASE INHIBITORS PHARMACIA ITALIA SPA (IT) 2002-10-24 — — WO claimed
US-4380629-A Styryl-like compounds showing a color-developing and bleaching behavior with improved stability and prolonged lifetime MATSUSHITA ELECTRIC INDUSTRIAL COMPANY, LIMITED (JP) 1983-04-19 — — US claimed
US-4147862-A Method of preparing styryl-like compounds MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1979-04-03 — — US claimed
EP-4663636-A2 TRIFLUOROMETHYL SUBSTITUTED PYRAZOLES AS HUMAN PLASMA KALLIKREIN INHIBITORS BioCryst Pharmaceuticals, Inc. (US) 2025-12-17 — — EP disclosed
US-20250270171-A1 HUMAN PLASMA KALLIKREIN INHIBITORS WILMINGTON TRUST, NATIONAL ASSOCIATION 2025-08-28 — — US disclosed
US-20250257040-A1 HUMAN PLASMA KALLIKREIN INHIBITORS WILMINGTON TRUST, NATIONAL ASSOCIATION 2025-08-14 — — US disclosed
EP-4180424-B1 SUBSTITUTED PYRAZOLES AS HUMAN PLASMA KALLIKREIN INHIBITORS BIOCRYST PHARM INC (US) 2025-06-25 — — EP disclosed
US-12162838-B2 Human plasma kallikrein inhibitors BIOCRYST PHARMACEUTICALS, INC. (US) 2024-12-10 — — US disclosed
US-12116346-B2 Human plasma kallikrein inhibitors BIOCRYST PHARMACEUTICALS, INC. (US) 2024-10-15 — — US disclosed
CN-118666661-A Alpha-hydroxy ketone long wavelength photoinitiator and preparation method and application thereof 北京化工大学 2024-09-20 — — CN disclosed
US-4371607-A 4-Halogeno-5-(halogenomethyl-phenyl)-oxazole derivatives, a process for the preparation thereof, and radiation-sensitive compositions containing these derivatives HOECHST AKTIENGESELLSCHAFT (DE) 1983-02-01 — — US disclosed
US-4314058-A Indolins styryl-like compounds MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1982-02-02 — — US disclosed
EP-0041675-A2 4-Halogen-5-(trichloromethyl-phenyl)-oxazole derivatives, process for preparing them and radiation-sensitive compositions containing them HOECHST AKTIENGESELLSCHAFT (DE) 1981-12-16 — — EP disclosed
US-4147862-A Method of preparing styryl-like compounds MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1979-04-03 — — US disclosed
US-4139274-A Apparatus for changing color MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1979-02-13 — — US disclosed
US-4090877-A COLOR PHOTOGRAPHY MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1978-05-23 — — US disclosed
US-4003633-A Color display device MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JA) 1977-01-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12116346-B2 Human plasma kallikrein inhibitors KLKB1, KLK5, KLK1 PADI4 524/4885MEN1 407/4885KMT2A 1644/4885
US-20250270171-A1 HUMAN PLASMA KALLIKREIN INHIBITORS KLKB1, KLK5, KLK1 PADI4 524/4885MEN1 407/4885KMT2A 1644/4885
US-20040132807-A1 Aurones as telomerase inhibitors TERT, TERF2, TERF2IP PADI4 2834/4885MEN1 1719/4885KMT2A 828/4885
US-20250257040-A1 HUMAN PLASMA KALLIKREIN INHIBITORS KLKB1, KLK5, KLK1 PADI4 524/4885MEN1 407/4885KMT2A 1644/4885
US-12162838-B2 Human plasma kallikrein inhibitors KLKB1, KLK5, KLK1 PADI4 524/4885MEN1 407/4885KMT2A 1644/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.