Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.42 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.42 |
| ▸ | ITGAL | P20701 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3484699 | 0.88 | NPC1 (0.49) | HPGDKMT2ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL29035080 | 0.86 | HPGD (0.54) | HPGDPOLBKMT2ACYP1A2CYP3A4 | |
| SCHEMBL16163251 | 0.84 | HPGD (0.56) | HPGDPOLBKMT2ACYP1A2CYP3A4 | |
| SCHEMBL16163257 | 0.84 | HPGD (0.52) | HPGDPOLBKMT2ACYP1A2CYP3A4 | |
| SCHEMBL23457081 | 0.82 | RAB9A (0.58) | HPGDPOLBKMT2ACYP1A2CYP3A4 | |
| SCHEMBL31682610 | 0.82 | RAB9A (0.58) | HPGDPOLBKMT2ACYP1A2CYP3A4 | |
| SCHEMBL4121932 | 0.81 | NPC1 (0.53) | HPGDKMT2ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL13761323 | 0.81 | MAPT (0.62) | HPGDPOLBKMT2AMAPTHTT | |
| SCHEMBL16162923 | 0.81 | HPGD (0.52) | HPGDPOLBKMT2ACYP1A2CYP3A4 | |
| SCHEMBL227238 | 0.80 | SMN1; SMN2 (0.59) | HPGDPOLBKMT2ACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9145364-B2 | Synthesis of psuedo indoxyl derivatives | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-09-29 | — | — | US | disclosed |
| US-20140309434-A1 | SYNTHESIS OF PSUEDO INDOXYL DERIVATIVES | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2014-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140309434-A1 | SYNTHESIS OF PSUEDO INDOXYL DERIVATIVES | IPO4, IPO11, IDO2 | HPGD 386/4885POLB 2683/4885KMT2A 1696/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.