Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.38 |
| ▸ | DPP4 | P27487 | 6/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 2/20 | 0.34 |
| ▸ | F10 | P00742 | 2/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14978021 | 0.93 | GPR119 (0.39) | GPR119KCNH2P2RX7 | |
| Trifluoroacetic Acid SCHEMBL14966698 | 0.85 | GPR119 (0.43) | GPR119KCNH2DPP4DPP7P2RX7 | |
| Trifluoroacetic Acid SCHEMBL16163342 | 0.84 | GPR119 (0.38) | GPR119KCNH2DPP4DPP7CYP2D6 | |
| SCHEMBL14970197 | 0.81 | GPR119 (0.55) | GPR119 | |
| SCHEMBL16172053 | 0.76 | TP53 (0.42) | GPR119KCNH2CYP2D6 | |
| SCHEMBL14968846 | 0.76 | GPR119 (0.42) | GPR119KCNH2NR1H2NR1H3 | |
| SCHEMBL16169607 | 0.76 | GPR119 (0.37) | GPR119KCNH2CYP2D6 | |
| SCHEMBL14966347 | 0.75 | KCNH2 (0.43) | GPR119KCNH2NR1H2NR1H3 | |
| Trifluoroacetic Acid SCHEMBL14966699 | 0.75 | GPR119 (0.38) | GPR119KCNH2DPP4DPP7CYP2D6 | |
| Trifluoroacetic Acid SCHEMBL16163152 | 0.74 | TP53 (0.37) | GPR119KCNH2DPP4DPP7F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140309226-A1 | PIPERIDINYL-SUBSTITUTED CYCLIC UREAS AS GPR119 MODULATORS | ARRAY BIOPHARMA, INC. | 2014-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140309226-A1 | PIPERIDINYL-SUBSTITUTED CYCLIC UREAS AS GPR119 MODULATORS | GPR119, UTS2R, GPR139 | GPR119 1/4885KCNH2 1308/4885DPP4 1179/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.