Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PSMD10 | O75832 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1681607 | 0.88 | STAT3 (0.43) | STAT3ALDH1A1KMT2ACA12CA1 | |
| SCHEMBL28931265 | 0.88 | STAT3 (0.43) | STAT3ALDH1A1KMT2ACA12CA1 | |
| Ethylene Glycol SCHEMBL1936214 | 0.82 | CA1 (0.48) | STAT3ALDH1A1KMT2ACA12CA1 | |
| SCHEMBL1258986 | 0.82 | STAT3 (0.47) | STAT3ALDH1A1KMT2ACA12CA1 | |
| SCHEMBL6573297 | 0.82 | STAT3 (0.49) | STAT3ALDH1A1KMT2ACA12CA1 | |
| SCHEMBL5792946 | 0.81 | L3MBTL1 (0.54) | STAT3ALDH1A1KMT2ACA12CA1 | |
| SCHEMBL17763488 | 0.81 | STAT3 (0.47) | STAT3ALDH1A1KMT2ACA12CA1 | |
| SCHEMBL10860607 | 0.80 | STAT3 (0.46) | STAT3ALDH1A1KMT2ACA12CA1 | |
| Ethylene SCHEMBL11280661 | 0.79 | STAT3 (0.44) | STAT3ALDH1A1KMT2ACA12CA1 | |
| Ethylene SCHEMBL7519766 | 0.79 | STAT3 (0.44) | STAT3ALDH1A1KMT2ACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3337475-B1 | NITROXIDE CONTAINING AMYLOID BINDING AGENTS FOR IMAGING AND THERAPEUTIC USES | UNIV CALIFORNIA (US) | 2024-10-02 | — | — | EP | disclosed |
| US-12064488-B2 | Nitroxide containing amyloid binding agents for imaging and therapeutic uses | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-08-20 | — | — | US | disclosed |
| US-20220202962-A1 | NITROXIDE CONTAINING AMYLOID BINDING AGENTS FOR IMAGING AND THERAPEUTIC USES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2022-06-30 | — | — | US | disclosed |
| US-10881748-B2 | Nitroxide containing amyloid binding agents for imaging and therapeutic uses | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-01-05 | — | — | US | disclosed |
| US-20200246492-A1 | NITROXIDE CONTAINING AMYLOID BINDING AGENTS FOR IMAGING AND THERAPEUTIC USES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2020-08-06 | — | — | US | disclosed |
| US-10478513-B2 | Nitroxide containing amyloid binding agents for imaging and therapeutic uses | THE REGENTS OF THE UNIVERSITY OF CALIFONIA (US) | 2019-11-19 | — | — | US | disclosed |
| US-20180221514-A1 | NITROXIDE CONTAINING AMYLOID BINDING AGENTS FOR IMAGING AND THERAPEUTIC USES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2018-08-09 | — | — | US | disclosed |
| EP-3337475-A1 | NITROXIDE CONTAINING AMYLOID BINDING AGENTS FOR IMAGING AND THERAPEUTIC USES | The Regents of The University of California (US) | 2018-06-27 | — | — | EP | disclosed |
| WO-2017031239-A1 | NITROXIDE CONTAINING AMYLOID BINDING AGENTS FOR IMAGING AND THERAPEUTIC USES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-02-23 | — | — | WO | disclosed |
| US-7923584-B2 | Synthesis of difunctional oxyethylene-based compounds | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2011-04-12 | — | — | US | disclosed |
| US-20090187037-A1 | SYNTHESIS OF DIFUNCTIONAL OXYETHYLENE-BASED COMPOUNDS | THE GOVERNMENT OF THE UNITED STATES, AS RESPRESENTED BY THE SECRETARY OF THE NAVY | 2009-07-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220202962-A1 | NITROXIDE CONTAINING AMYLOID BINDING AGENTS FOR IMAGING AND THERAPEUTIC USES | APP, APBA1, CRYAB | STAT3 4709/4885ALDH1A1 3820/4885KMT2A 4406/4885 |
| US-10881748-B2 | Nitroxide containing amyloid binding agents for imaging and therapeutic uses | APP, APBA1, CRYAB | STAT3 4709/4885ALDH1A1 3820/4885KMT2A 4406/4885 |
| US-10478513-B2 | Nitroxide containing amyloid binding agents for imaging and therapeutic uses | APP, APBA1, CRYAB | STAT3 4709/4885ALDH1A1 3820/4885KMT2A 4406/4885 |
| US-20090187037-A1 | SYNTHESIS OF DIFUNCTIONAL OXYETHYLENE-BASED COMPOUNDS | RPS24, RPL24, BRIX1 | STAT3 2105/4885ALDH1A1 3773/4885KMT2A 1703/4885 |
| US-12064488-B2 | Nitroxide containing amyloid binding agents for imaging and therapeutic uses | APP, APBA1, CRYAB | STAT3 4709/4885ALDH1A1 3820/4885KMT2A 4406/4885 |
| US-20180221514-A1 | NITROXIDE CONTAINING AMYLOID BINDING AGENTS FOR IMAGING AND THERAPEUTIC USES | APP, APBA1, CRYAB | STAT3 4722/4885ALDH1A1 3882/4885KMT2A 4490/4885 |
| US-20200246492-A1 | NITROXIDE CONTAINING AMYLOID BINDING AGENTS FOR IMAGING AND THERAPEUTIC USES | APP, APBA1, CRYAB | STAT3 4709/4885ALDH1A1 3820/4885KMT2A 4406/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.