SCHEMBL16166011

SCHEMBL16166011

O=C(O)c1ccc(-c2cccc(-c3ccc(C(=O)O)cc3)c2)cc1

nearest known ligand 0.77

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMO O15229 1/20 0.72
EGFR P00533 1/20 0.70
TRIM24 O15164 1/20 0.69
TRIM33 Q9UPN9 1/20 0.69
RXRA P19793 6/20 0.67
RXRB P28702 6/20 0.67
RXRG P48443 1/20 0.67
BCL2 P10415 1/20 0.67
RARA P10276 1/20 0.62
RARB P10826 1/20 0.62
RARG P13631 1/20 0.62
DHODH Q02127 1/20 0.58
BCL2L1 Q07817 1/20 0.58
BAD Q92934 1/20 0.58
TP53 P04637 1/20 0.57
TSHR P16473 1/20 0.57
ACMSD Q8TDX5 1/20 0.57
MKNK1 Q9BUB5 1/20 0.57
MKNK2 Q9HBH9 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30066684 1.00 KMO (0.72) KMOEGFRTRIM24TRIM33RXRA
SCHEMBL29906143 0.98 KMO (0.76) KMOEGFRTRIM24TRIM33RXRA
SCHEMBL2346605 0.98 KMO (0.76) KMOEGFRTRIM24TRIM33RXRA
SCHEMBL27607318 0.93 TSHR (0.67) KMOEGFRTRIM24TRIM33RXRA
SCHEMBL16166084 0.92 DHODH (0.71) KMOEGFRTRIM24TRIM33RXRA
SCHEMBL30610358 0.92 DHODH (0.71) KMOEGFRTRIM24TRIM33RXRA
SCHEMBL16166225 0.92 KMO (0.81) KMOEGFRTRIM24TRIM33RXRA
SCHEMBL69066 0.91 KMO (0.80) KMOEGFRTRIM24TRIM33RXRA
SCHEMBL3551496 0.91 KMO (0.80) KMOEGFRTRIM24TRIM33RXRA
SCHEMBL29904703 0.91 KMO (0.80) KMOEGFRTRIM24TRIM33RXRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260008900-A1 RUBBER ASPHALT-DERIVED VOLATILE ORGANIC COMPOUNDS (VOCs) INHIBITOR BASED ON METAL ORGANIC FRAMEWORKS (MOFs) MATERIAL AND PREPARATION METHOD THEREOF, AND SMOKE-SUPPRESSION RUBBER ASPHALT AND PREPARATION METHOD THEREOF UNIV WUHAN TECH (CN) 2026-01-08 US claimed
EP-4585600-A1 RETICULAR DESIGN AND DEVELOPMENT OF HIGHLY POROUS METAL-ORGANIC FRAMEWORKS FOR GAS AND VAPOR SORPTION APPLICATIONS Special Account for Research Funds of University of Crete (SARF UoC) (GR) 2025-07-16 EP claimed
CN-118994612-A Sheet zirconium-based metal organic framework material Zr-MOF, and preparation method and application thereof 中山大学 2024-11-22 CN claimed
CN-118652438-A Zirconium-based metal organic framework and preparation method thereof 深圳职业技术大学 2024-09-17 CN claimed
EP-4397399-A2 MEMBRANES COMPRISING A LAYER OF METAL ORGANIC FRAMEWORK PARTICLES G2O Water Technologies Limited (GB) 2024-07-10 EP claimed
CN-115825273-A Detection method for organic chlorine pesticide in water body based on MOSS material solid phase micro-extraction 南京大学 2023-03-21 CN claimed
CN-115246923-A Wide-color-gamut high-performance fluorescent copolyester and synthesis method and application thereof 中国科学院化学研究所 2022-10-28 CN claimed
CN-112940268-B Interface in-situ growth metal-organic framework material and preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2022-04-12 CN claimed
US-20260008900-A1 RUBBER ASPHALT-DERIVED VOLATILE ORGANIC COMPOUNDS (VOCs) INHIBITOR BASED ON METAL ORGANIC FRAMEWORKS (MOFs) MATERIAL AND PREPARATION METHOD THEREOF, AND SMOKE-SUPPRESSION RUBBER ASPHALT AND PREPARATION METHOD THEREOF UNIV WUHAN TECH (CN) 2026-01-08 US disclosed
EP-4585600-A1 RETICULAR DESIGN AND DEVELOPMENT OF HIGHLY POROUS METAL-ORGANIC FRAMEWORKS FOR GAS AND VAPOR SORPTION APPLICATIONS Special Account for Research Funds of University of Crete (SARF UoC) (GR) 2025-07-16 EP disclosed
US-20250188521-A1 NUCLEIC ACID DELIVERY SCAFFOLDS Singular Genomics Systems, Inc. 2025-06-12 US disclosed
CN-119823403-A Preparation method and application of dual-ligand MOF photocatalyst 中国石油大学(华东) 2025-04-15 CN disclosed
US-12188088-B1 Multiplexed targeted amplification of polynucleotides Singular Genomics Systems, Inc. (US) 2025-01-07 US disclosed
US-20240424488-A1 High-Entropy Metal-Organic Frameworks NATIONAL TECHNOLOGY & ENGINEERING SOLUTIONS OF SANDIA, LLC 2024-12-26 US disclosed
CN-115246923-A Wide-color-gamut high-performance fluorescent copolyester and synthesis method and application thereof 中国科学院化学研究所 2022-10-28 CN disclosed
CN-112940268-B Interface in-situ growth metal-organic framework material and preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2022-04-12 CN disclosed
CN-110498928-A A kind of pair of Minim Benzene in Gas Phase system object has the metal-organic framework material of efficient absorption removal capacity UNIV BEIJING TECHNOLOGY 2019-11-26 CN disclosed
US-20160060434-A1 STABILIZATION OF POLYAMIDE WITH COPPER-BASED METAL ORGANIC FRAMEWORKS BASF SE (DE) 2016-03-03 US disclosed
EP-2984131-A1 STABILIZATION OF POLYAMIDE WITH COPPER-BASED METAL ORGANIC FRAMEWORKS BASF SE (DE) 2016-02-17 EP disclosed
WO-2014166865-A1 STABILIZATION OF POLYAMIDE WITH COPPER-BASED METAL ORGANIC FRAMEWORKS BASF SE (DE) 2014-10-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260008900-A1 RUBBER ASPHALT-DERIVED VOLATILE ORGANIC COMPOUNDS (VOCs) INHIBITOR BASED ON METAL ORGANIC FRAMEWORKS (MOFs) MATERIAL AND PREPARATION METHOD THEREOF, AND SMOKE-SUPPRESSION RUBBER ASPHALT AND PREPARATION METHOD THEREOF MCM6, KAT6A, SUV39H2 KMO 1135/4885EGFR 294/4885TRIM24 412/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.