Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 16/20 | 1.00 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.71 |
| ▸ | TTR | P02766 | 1/20 | 0.71 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.71 |
| ▸ | MAPT | P10636 | 1/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16166211 | 1.00 | ABCB1 (1.00) | ABCB1PDPK1TTRALOX5MAPT | |
| SCHEMBL144848 | 0.91 | ABCB1 (0.85) | ABCB1PDPK1TTRALOX5MAPT | |
| SCHEMBL17585476 | 0.90 | ABCB1 (0.84) | ABCB1PDPK1TTRALOX5MAPT | |
| SCHEMBL5519605 | 0.90 | ABCB1 (1.00) | ABCB1PDPK1TTRALOX5 | |
| SCHEMBL5519601 | 0.90 | ABCB1 (1.00) | ABCB1PDPK1TTRALOX5 | |
| SCHEMBL17583538 | 0.90 | ABCB1 (0.81) | ABCB1PDPK1TTRALOX5MAPT | |
| SCHEMBL17583539 | 0.90 | ABCB1 (0.81) | ABCB1PDPK1TTRALOX5MAPT | |
| SCHEMBL30630210 | 0.86 | PDPK1 (0.93) | ABCB1PDPK1TTRALOX5MAPT | |
| SCHEMBL26539037 | 0.86 | PDPK1 (0.93) | ABCB1PDPK1TTRALOX5MAPT | |
| Xanthohumol SCHEMBL30169731 | 0.83 | PDPK1 (1.00) | ABCB1PDPK1TTRALOX5MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9617213-B2 | Synthetic analogues of xanthohumol | UNIVERSITA' DI PISA (IT) | 2017-04-11 | — | — | US | claimed |
| US-20160075652-A1 | SYNTHETIC ANALOGUES OF XANTHOHUMOL | AZIENDA OSPEDALIERA DI REGGIO EMILIA ARCISPEDALE S. MARIA NUOVA IRCCS (IT) | 2016-03-17 | — | — | US | claimed |
| EP-2984072-A1 | SYNTHETIC ANALOGUES OF XANTHOHUMOL | Universita Di Pisa (IT) | 2016-02-17 | — | — | EP | claimed |
| WO-2014167481-A1 | SYNTHETIC ANALOGUES OF XANTHOHUMOL | UNIVERSITA' DI PISA (IT) | 2014-10-16 | — | — | WO | claimed |
| US-9617213-B2 | Synthetic analogues of xanthohumol | UNIVERSITA' DI PISA (IT) | 2017-04-11 | — | — | US | disclosed |
| US-20160075652-A1 | SYNTHETIC ANALOGUES OF XANTHOHUMOL | AZIENDA OSPEDALIERA DI REGGIO EMILIA ARCISPEDALE S. MARIA NUOVA IRCCS (IT) | 2016-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160075652-A1 | SYNTHETIC ANALOGUES OF XANTHOHUMOL | XDH, XPA, NR1H3 | ABCB1 4197/4885PDPK1 3213/4885TTR 4577/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.