Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | CDC25B | P30305 | 1/20 | 0.44 |
| ▸ | USP8 | P40818 | 1/20 | 0.42 |
| ▸ | USP7 | Q93009 | 1/20 | 0.42 |
| ▸ | BCL2 | P10415 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | APAF1 | O14727 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | PTPRC | P08575 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TDP2 | O95551 | 2/20 | 0.38 |
| ▸ | S100A4 | P26447 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28705 | 0.73 | STAT3 (0.56) | STAT3ALDH1A1KMT2AMEN1CDC25B | |
| SCHEMBL6577994 | 0.73 | STAT3 (0.61) | STAT3ALDH1A1KMT2AMEN1CDC25B | |
| SCHEMBL16167166 | 0.73 | STAT3 (0.56) | STAT3ALDH1A1KMT2AMEN1CDC25B | |
| SCHEMBL19669614 | 0.72 | STAT3 (0.59) | STAT3ALDH1A1KMT2AMEN1CDC25B | |
| SCHEMBL29365382 | 0.70 | STAT3 (0.69) | STAT3ALDH1A1KMT2AMEN1CDC25B | |
| SCHEMBL30422 | 0.70 | STAT3 (0.57) | STAT3ALDH1A1KMT2AMEN1CDC25B | |
| SCHEMBL12640092 | 0.70 | STAT3 (0.53) | STAT3ALDH1A1KMT2AMEN1CDC25B | |
| SCHEMBL1887185 | 0.70 | STAT3 (0.69) | STAT3ALDH1A1KMT2AMEN1CDC25B | |
| SCHEMBL10068407 | 0.70 | ALDH1A1 (0.53) | STAT3ALDH1A1KMT2AMEN1CDC25B | |
| Anthraquinone SCHEMBL7142334 | 0.70 | MEN1 (0.80) | ALDH1A1KMT2AMEN1CDC25BUSP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3153508-A1 | NOVEL ANTICANCER AGENT | Kyoto Pharmaceutical Industries, Ltd. (JP) | 2017-04-12 | — | — | EP | disclosed |