Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | APAF1 | O14727 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | S100A4 | P26447 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | Q9HBH1 | 3/20 | 0.39 | |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29362140 | 0.82 | MAPT (0.68) | MAPTALDH1A1KMT2AMEN1HTT | |
| SCHEMBL14657071 | 0.82 | MAPT (0.68) | MAPTALDH1A1KMT2AMEN1HTT | |
| SCHEMBL29365255 | 0.72 | STAT3 (0.69) | MAPTALDH1A1KMT2AMEN1HTT | |
| SCHEMBL1882564 | 0.72 | STAT3 (0.69) | MAPTALDH1A1KMT2AMEN1HTT | |
| Acetone SCHEMBL28257736 | 0.69 | S100A4 (0.71) | MAPTALDH1A1KMT2AMEN1MAPK1 | |
| SCHEMBL14439661 | 0.68 | ALDH1A1 (0.48) | MAPTALDH1A1KMT2AMEN1MAPK1 | |
| SCHEMBL29892465 | 0.67 | MAPT (0.68) | MAPTALDH1A1KMT2AMEN1HTT | |
| SCHEMBL27157150 | 0.67 | MAPT (0.68) | MAPTALDH1A1KMT2AMEN1HTT | |
| SCHEMBL353693 | 0.67 | S100A4 (0.80) | ALDH1A1KMT2AMEN1MAPK1TDP1 | |
| SCHEMBL4229683 | 0.67 | S100A4 (0.80) | ALDH1A1KMT2AMEN1MAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2983790-A2 | METHODS FOR TREATING CANCER | Boston Biomedical, Inc. (US) | 2016-02-17 | — | — | EP | disclosed |
| WO-2014169078-A2 | METHODS FOR TREATING CANCER | BOSTON BIOMEDICAL, INC. (US) | 2014-10-16 | — | — | WO | disclosed |