Styrene

Styrene

SCHEMBL16167382

C=C.C=CC(C)c1ccccc1.C=Cc1ccccc1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.56
TSHR P16473 2/20 0.56
TRPA1 O75762 3/20 0.39
PTGS2 P35354 1/20 0.37
ADRA2C P18825 2/20 0.36
KDM4E B2RXH2 2/20 0.36
ADRA2A P08913 1/20 0.36
LMNA P02545 1/20 0.36
HIF1A Q16665 1/20 0.36
TP53 P04637 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
HDAC8 Q9BY41 2/20 0.34
CHRM2 P08172 1/20 0.34
ADRA1A P35348 1/20 0.34
RGS12 O14924 1/20 0.34
GLA P06280 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C9 P11712 1/20 0.34
PKM P14618 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL8948454 0.98 ALDH1A1 (0.58) ALDH1A1TSHRTRPA1PTGS2ADRA2C
SCHEMBL7808281 0.87 TRPA1 (0.47) ALDH1A1TSHRTRPA1ADRA2CKDM4E
SCHEMBL132606 0.87 TRPA1 (0.47) ALDH1A1TSHRTRPA1ADRA2CKDM4E
SCHEMBL9719434 0.87 TRPA1 (0.47) ALDH1A1TSHRTRPA1ADRA2CKDM4E
Isopropylbenzene SCHEMBL27427371 0.81 ALDH1A1 (0.64) ALDH1A1TSHRPTGS2ADRA2CKDM4E
Styrene SCHEMBL27365171 0.81 ALDH1A1 (0.64) ALDH1A1TSHRPTGS2ADRA2CKDM4E
Styrene SCHEMBL27353595 0.81 ALDH1A1 (0.70) ALDH1A1TSHRPTGS2LMNATP53
Styrene SCHEMBL27612971 0.81 ALDH1A1 (0.70) ALDH1A1TSHRPTGS2LMNATP53
Styrene SCHEMBL27201704 0.80 ALDH1A1 (0.78) ALDH1A1TSHRPTGS2LMNATP53
Styrene SCHEMBL28134369 0.80 ALDH1A1 (0.78) ALDH1A1TSHRPTGS2LMNATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2984055-A1 PREPARATION OF SURFACTANTS VIA CROSS-METATHESIS Materia, Inc. (US) 2016-02-17 EP disclosed
WO-2015126462-A1 PREPARATION OF SURFACTANTS VIA CROSS-METATHESIS MATERIA, INC. (US) 2015-08-27 WO disclosed
WO-2014169080-A1 PREPARATION OF SURFACTANTS VIA CROSS-METATHESIS MATERIA, INC. (US) 2014-10-16 WO disclosed