Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 3/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL132606 | 1.00 | TRPA1 (0.47) | TRPA1TAAR1LMNAADRA2AADRA2C | |
| SCHEMBL9719434 | 1.00 | TRPA1 (0.47) | TRPA1TAAR1LMNAADRA2AADRA2C | |
| SCHEMBL27866699 | 0.89 | TRPA1 (0.44) | TRPA1LMNAADRA2AADRA2CHIF1A | |
| Styrene SCHEMBL8948454 | 0.89 | ALDH1A1 (0.58) | TRPA1LMNAADRA2AADRA2CCYP2D6 | |
| Styrene SCHEMBL16167382 | 0.87 | ALDH1A1 (0.56) | TRPA1LMNAADRA2AADRA2CCYP2D6 | |
| SCHEMBL7775718 | 0.80 | TRPA1 (0.44) | TRPA1TAAR1LMNAADRA2AADRA2C | |
| SCHEMBL4107537 | 0.79 | TYR (0.46) | LMNACYP2D6HIF1AKDM4E | |
| SCHEMBL6860167 | 0.79 | TRPA1 (0.47) | TRPA1TAAR1LMNAADRA2AADRA2C | |
| SCHEMBL5466658 | 0.78 | TSHR (0.39) | TRPA1TAAR1LMNAKDM4EALDH1A1 | |
| SCHEMBL9474715 | 0.78 | TRPA1 (0.34) | TRPA1TAAR1LMNAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647647-B1 | Tertiary phosphine compound and transition metal complex comprising the same as ligand | SUMITOMO CHEMICAL CO (JP) | 2001-10-24 | — | — | EP | disclosed |
| US-5523437-A | Tertiary phosphine compound and transition metal complex comprising the same as ligand | SUMITOMO CHEMICAL CO., LTD. (JP) | 1996-06-04 | — | — | US | disclosed |
| EP-0647647-A1 | Tertiary phosphine compound and transition metal complex comprising the same as ligand | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-04-12 | — | — | EP | disclosed |
| EP-0247595-B1 | NEW AZAPHOSPHOLONES AND USE THEREOF | Studiengesellschaft Kohle mbH (DE) | 1992-01-02 | — | — | EP | disclosed |
| US-4912274-A | Azaphospholenes and use thereof | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 1990-03-27 | — | — | US | disclosed |
| US-4900866-A | Azaphospholenes | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 1990-02-13 | — | — | US | disclosed |
| US-4827067-A | Azaphospholenes and use thereof | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 1989-05-02 | — | — | US | disclosed |
| EP-0247595-A2 | New azaphospholones and use thereof | Studiengesellschaft Kohle mbH (DE) | 1987-12-02 | — | — | EP | disclosed |