Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.36 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 3/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | TACR2 | P21452 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.34 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16167675 | 0.87 | ALDH1A1 (0.39) | HSD11B1L3MBTL1AVPR1AALDH1A1KMT2A | |
| SCHEMBL7911467 | 0.87 | ALDH1A1 (0.39) | HSD11B1L3MBTL1AVPR1ASMN1; SMN2ALDH1A1 | |
| SCHEMBL2511918 | 0.85 | HSD11B1 (0.46) | HSD11B1SMN1; SMN2ALDH1A1CNR1KMT2A | |
| SCHEMBL7908197 | 0.84 | ALDH1A1 (0.38) | HSD11B1AVPR1AALDH1A1KMT2A | |
| SCHEMBL7914828 | 0.84 | AVPR1A (0.39) | HSD11B1AVPR1ASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL16167674 | 0.83 | AVPR1A (0.37) | HSD11B1AVPR1ASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL7909318 | 0.83 | AVPR1A (0.37) | HSD11B1L3MBTL1AVPR1AALDH1A1CNR2 | |
| SCHEMBL7908194 | 0.83 | KMT2A (0.38) | HSD11B1AVPR1AALDH1A1CNR2KMT2A | |
| SCHEMBL2500560 | 0.82 | AVPR2 (0.41) | HSD11B1AVPR1ASMN1; SMN2KMT2ASMPD1 | |
| SCHEMBL2513400 | 0.82 | RXFP1 (0.37) | HSD11B1L3MBTL1AVPR1ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8859601-B2 | Substituted benzyl and phenylsulfonyl triazolones, and use thereof | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-10-14 | — | — | US | disclosed |
| US-8859601-B2 | Substituted benzyl and phenylsulfonyl triazolones, and use thereof | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-10-14 | — | — | US | disclosed |