Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 11/20 | 0.52 |
| ▸ | MTNR1B | P49286 | 10/20 | 0.52 |
| ▸ | PPARD | Q03181 | 2/20 | 0.51 |
| ▸ | NQO2 | P16083 | 6/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13938781 | 0.85 | MTNR1A (0.66) | MTNR1AMTNR1BPPARDNQO2 | |
| SCHEMBL7950050 | 0.85 | MTNR1A (0.66) | MTNR1AMTNR1BPPARDNQO2 | |
| SCHEMBL8884747 | 0.83 | MTNR1A (0.61) | MTNR1AMTNR1BPPARDNQO2 | |
| SCHEMBL6641318 | 0.82 | ITGB3 (0.63) | MTNR1AMTNR1BPPARD | |
| SCHEMBL503654 | 0.81 | SIGMAR1 (0.57) | MTNR1AMTNR1BPPARD | |
| SCHEMBL24650762 | 0.80 | MTNR1A (0.45) | MTNR1AMTNR1BPPARDNQO2 | |
| SCHEMBL7175871 | 0.80 | PPARD (0.46) | MTNR1AMTNR1BPPARD | |
| SCHEMBL3413664 | 0.79 | MTNR1A (0.44) | MTNR1AMTNR1BPPARDNQO2 | |
| SCHEMBL3408615 | 0.79 | ESR1 (0.45) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL7172934 | 0.79 | PPARD (0.49) | MTNR1AMTNR1BPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5194437-A | Substituted with oxygen containing heterocycle, central nervous system disorders, neuroendocrine disorders | ADIR ET COMPAGNIE (FR) | 1993-03-16 | — | — | US | disclosed |