Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 14/20 | 0.40 |
| ▸ | CASP3 | P42574 | 2/20 | 0.38 |
| ▸ | IL1B | P01584 | 2/20 | 0.35 |
| ▸ | GNPAT | O15228 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18133071 | 0.89 | BMP1 (0.48) | CASP1CASP3GNPAT | |
| SCHEMBL21732968 | 0.88 | GNPAT (0.35) | CASP1CASP3IL1BGNPAT | |
| SCHEMBL16168241 | 0.84 | MME (0.39) | CASP1GNPAT | |
| SCHEMBL9924421 | 0.79 | CTSK (0.38) | CASP1 | |
| SCHEMBL6853153 | 0.78 | — | — | |
| SCHEMBL12683542 | 0.78 | — | — | |
| SCHEMBL20342120 | 0.78 | — | — | |
| SCHEMBL11956575 | 0.77 | GNPAT (0.49) | GNPAT | |
| SCHEMBL5668501 | 0.76 | PAX8 (0.46) | CASP1CASP3IL1B | |
| SCHEMBL25583190 | 0.76 | PAX8 (0.46) | CASP1CASP3IL1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2789342-A1 | TDF-related compounds and analogs thereof | Thrasos Innovation, Inc. (CA) | 2014-10-15 | — | — | EP | disclosed |