Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | RORC | P51449 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | G6PD | P11413 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14430167 | 0.92 | TSHR (0.50) | TSHRRORCPKMALDH1A1HPGD | |
| SCHEMBL1244536 | 0.89 | TSHR (0.52) | TSHRRORCPKMALDH1A1HPGD | |
| SCHEMBL11705699 | 0.88 | TSHR (0.50) | TSHRRORCPKMALDH1A1HPGD | |
| SCHEMBL1245470 | 0.88 | TSHR (0.50) | TSHRRORCPKMALDH1A1HPGD | |
| SCHEMBL7762441 | 0.84 | TSHR (0.60) | TSHRRORCPKMALDH1A1HPGD | |
| SCHEMBL11705430 | 0.83 | TSHR (0.50) | TSHRRORCPKMALDH1A1HPGD | |
| SCHEMBL16736577 | 0.79 | RORC (0.46) | TSHRRORCPKMALDH1A1HPGD | |
| SCHEMBL574476 | 0.79 | LMNA (0.67) | TSHRRORCPKMALDH1A1HPGD | |
| SCHEMBL16736806 | 0.79 | TSHR (0.46) | TSHRRORCPKMALDH1A1HPGD | |
| SCHEMBL16736901 | 0.79 | TSHR (0.46) | TSHRRORCPKMALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2332909-B1 | HYDROXYBENZAMIDE DERIVATIVES AND THEIR USE AS INHIBITORS OF HSP90 | ASTEX THERAPEUTICS LTD (GB) | 2014-10-15 | — | — | EP | disclosed |