SCHEMBL574476

SCHEMBL574476

CCC(C)c1cc(Cl)c(C)cc1O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.67
RORC P51449 1/20 0.46
TSHR P16473 1/20 0.46
PKM P14618 2/20 0.37
ALDH1A1 P00352 3/20 0.37
GAA P10253 2/20 0.37
KDM4E B2RXH2 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
THRA P10827 1/20 0.36
THRB P10828 1/20 0.36
ALOX15 P16050 2/20 0.36
USP2 O75604 1/20 0.36
HPGD P15428 1/20 0.36
HSD17B10 Q99714 1/20 0.36
ALOX12 P18054 1/20 0.35
HDAC4 P56524 1/20 0.34
HDAC2 Q92769 1/20 0.34
HDAC8 Q9BY41 1/20 0.34
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6910713 0.87 LMNA (0.51) LMNARORCTSHRPKMALDH1A1
SCHEMBL7863389 0.85 LMNA (0.54) LMNARORCTSHRPKMALDH1A1
SCHEMBL15944087 0.85 LMNA (0.52) LMNARORCTSHRPKMALDH1A1
SCHEMBL16736873 0.85 RORC (0.49) LMNARORCTSHRPKMALDH1A1
SCHEMBL1244536 0.84 TSHR (0.52) LMNARORCTSHRPKMALDH1A1
SCHEMBL574295 0.83 LMNA (0.63) LMNATSHRPKMALDH1A1GAA
SCHEMBL14430167 0.82 TSHR (0.50) LMNARORCTSHRPKMALDH1A1
SCHEMBL11705430 0.82 TSHR (0.50) LMNARORCTSHRPKMALDH1A1
SCHEMBL16736811 0.81 LMNA (0.52) LMNARORCTSHRPKMALDH1A1
SCHEMBL29984916 0.80 LMNA (0.56) LMNAPKMALDH1A1GAAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 609 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140135297-A1 AQUEOUS VOLATILE ORGANIC COMPOUND FREE DISINFECTANT AND/OR CLEANING COMPOSITION AND METHOD OF PREPARATION ISP INVESTMENTS INC. (US) 2014-05-15 US claimed
EP-2313026-A1 ACTIVE DELIVERY SYSTEM FORMULATIONS Castle Beach, L.L.C. (US) 2011-04-27 EP claimed
US-20100040565-A1 ACTIVE DELIVERY SYSTEMS FORMULATIONS Castle Beach, LLC (US) 2010-02-18 US claimed
WO-2010019680-A1 ACTIVE DELIVERY SYSTEM FORMULATIONS HOMOLA ANDREW M (US) 2010-02-18 WO claimed
US-20090214606-A1 ANTIMICROBIAL POROUS SILICON OXIDE PARTICLES CIBA SPECIALTY CHEMICALS CORP. 2009-08-27 US claimed
EP-1549731-B1 CLEANING AND DISINFECTING COMPOSITION RECKITT BENCKISER INC (US) 2008-12-17 EP claimed
US-20070231295-A1 Antimicrobial Silicon Oxide Flakes CIBA SPECIALTY CHEMICALS CORP. 2007-10-04 US claimed
EP-1755381-A2 ANTIMICROBIAL SILICON OXIDE FLAKES CIBA SPECIALTY CHEMICALS HOLDING INC. Patent Departement (CH) 2007-02-28 EP claimed
US-20060093570-A1 Surface treatment RECKITT BENCKISER (UK) LIMITED (GB) 2006-05-04 US claimed
US-20060040847-A1 Hard surface treating compositions RECKITT BENCKISER INC. 2006-02-23 US claimed
US-20060034880-A1 Cleaning and disinfecting composition RECKITT BENCKISER INC (US) 2006-02-16 US claimed
WO-2005107456-A2 ANTIMICROBIAL SILICON OXIDE FLAKES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2005-11-17 WO claimed
US-20050233930-A1 Disinfectant cleaning compositions RECKITT BENCKISER INC. (US) 2005-10-20 US claimed
EP-1537201-A1 HARD SURFACE TREATING COMPOSITIONS Reckitt Benckiser Inc. (US) 2005-06-08 EP claimed
EP-0805672-B1 METHODS, COMPOSITIONS, AND DENTAL DELIVERY SYSTEMS FOR THE PROTECTION OF THE SURFACES OF TEETH HOMOLA ANDREW M (US) 2004-08-25 EP claimed
WO-2004024861-A1 HARD SURFACE TREATING COMPOSITIONS RECKITT BENCKISER INC (US) 2004-03-25 WO claimed
US-5665333-A Methods, compositions, and dental delivery systems for the protection of the surfaces of teeth PROVSEAL LLC 1997-09-09 US claimed
US-12496344-B2 Biophotonic materials and uses thereof FLE INT S R L (IT) 2025-12-16 US disclosed
CN-1081366-A Antibacterial antiplaque oral composition COLGATE PALMOLIVE CO (US) 1994-02-02 CN disclosed
CN-1044047-A ANTIPLAQUE ANTIBACTERIAL ORAL COMPOSITION COLGATE PALMOLIVE CO (US) 1990-07-25 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100040565-A1 ACTIVE DELIVERY SYSTEMS FORMULATIONS LIPA, MMP7, CTSA LMNA 413/4885RORC 1883/4885TSHR 2621/4885
US-20060034880-A1 Cleaning and disinfecting composition APOBEC3G, APOBEC3C, APOBEC3B LMNA 2556/4885RORC 4797/4885TSHR 3974/4885
US-20070231295-A1 Antimicrobial Silicon Oxide Flakes SIK2, SIK3, SIK1 LMNA 4300/4885RORC 3634/4885TSHR 4621/4885
US-20090214606-A1 ANTIMICROBIAL POROUS SILICON OXIDE PARTICLES ORAI3, PRF1, THPO LMNA 4072/4885RORC 2984/4885TSHR 4256/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.