Sugi Predict

Sugi Predict / Compounds / SCHEMBL1616968

SCHEMBL1616968

SCHEMBL1616968

O=C1CCCCC1c1ccccn1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 6/20 0.60
▸ KDM4E B2RXH2 3/20 0.60
▸ DDB1 Q16531 1/20 0.54
▸ CRBN Q96SW2 1/20 0.54
▸ MAPT P10636 5/20 0.47
▸ TP53 P04637 2/20 0.47
▸ ALOX12 P18054 1/20 0.47
▸ SMN1; SMN2 Q16637 1/20 0.47
▸ L3MBTL1 Q9Y468 1/20 0.47
▸ KMT2A Q03164 3/20 0.43
▸ RAB9A P51151 2/20 0.43
▸ NPC1 O15118 1/20 0.43
▸ MCL1 Q07820 1/20 0.40
▸ TLR4 O00206 1/20 0.39
▸ SRC P12931 1/20 0.38
▸ HCAR1 Q9BXC0 2/20 0.38
▸ GFER P55789 1/20 0.37
▸ MEN1 O00255 1/20 0.36
▸ LMNA P02545 1/20 0.36
▸ NPSR1 Q6W5P4 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30853687 1.00 ALDH1A1 (0.60) ALDH1A1KDM4EDDB1CRBNMAPT
SCHEMBL30853698 1.00 ALDH1A1 (0.60) ALDH1A1KDM4EDDB1CRBNMAPT
SCHEMBL29711760 0.98 ALDH1A1 (0.59) ALDH1A1KDM4EDDB1CRBNMAPT
SCHEMBL29742364 0.98 ALDH1A1 (0.59) ALDH1A1KDM4EDDB1CRBNMAPT
SCHEMBL4129452 0.98 ALDH1A1 (0.59) ALDH1A1KDM4EDDB1CRBNMAPT
SCHEMBL29742353 0.98 ALDH1A1 (0.59) ALDH1A1KDM4EDDB1CRBNMAPT
SCHEMBL4963182 0.95 DDB1 (0.55) ALDH1A1KDM4EDDB1CRBNMAPT
SCHEMBL3664235 0.82 ALDH1A1 (0.44) ALDH1A1KDM4EDDB1CRBNMAPT
SCHEMBL9877946 0.78 DDB1 (0.53) ALDH1A1KDM4EDDB1CRBNMAPT
SCHEMBL11033988 0.77 ALDH1A1 (0.56) ALDH1A1KDM4EDDB1CRBNMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117903043-A Preparation method of cis-2-pyridine-2-yl cyclohexanol 武威广达科技有限公司 2024-04-19 — — CN claimed
EP-1050531-B1 Pyridine and piperidine derivatives for treating neurodegenerative diseases SERVIER LAB (FR) 2004-11-17 — — EP claimed
US-20030181484-A1 New substituted pyridine or piperidine compounds METH-COHN OTTO (GB) 2003-09-25 — — US claimed
US-20030139408-A1 Substituted pyridine or piperidine compounds METH-COHN OTTO (GB) 2003-07-24 — — US claimed
US-20020040036-A1 New substituted pyridine or piperidine compounds ADIR ET COMPAGNIE 2002-04-04 — — US claimed
US-20020035123-A1 New substituted pyridine or piperidine compounds ADIR ET COMPAGNIE 2002-03-21 — — US claimed
US-6323220-B1 COGNITION ACTIVATORS AND TREATMENT OF NERVOUS SYSTEM DISORDERS ADIR ET COMPAGNIE (FR) 2001-11-27 — — US claimed
EP-1050531-A1 Pyridine and piperidine derivatives for treating neurodegenerative diseases ADIR ET COMPAGNIE (FR) 2000-11-08 — — EP claimed
US-20240158340-A1 PHOTOCATALYTIC ARYLATION OF CARBONYL COMPOUNDS AND METHODS FOR USING THE SAME ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA 2024-05-16 — — US disclosed
CN-117903043-A Preparation method of cis-2-pyridine-2-yl cyclohexanol 武威广达科技有限公司 2024-04-19 — — CN disclosed
CN-117903043-A Preparation method of cis-2-pyridine-2-yl cyclohexanol 武威广达科技有限公司 2024-04-19 — — CN disclosed
WO-2022235875-A1 PHOTOCATALYTIC ARYLATION OF CARBONYL COMPOUNDS AND METHODS FOR USING THE SαAME ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2022-11-10 — — WO disclosed
US-8436005-B2 Macrocyclic pyrimidine derivatives ABBOTT LABORATORIES (US) 2013-05-07 — — US disclosed
WO-2012030952-A3 REDUCING RIPPLE CURRENT IN A SWITCHED-MODE POWER CONVERTER EMPLOYING A BRIDGE TOPOLOGY TEXAS INSTRUMENTS INCORPORATED (US) 2012-05-10 — — WO disclosed
US-20020035123-A1 New substituted pyridine or piperidine compounds ADIR ET COMPAGNIE 2002-03-21 — — US disclosed
US-6323220-B1 COGNITION ACTIVATORS AND TREATMENT OF NERVOUS SYSTEM DISORDERS ADIR ET COMPAGNIE (FR) 2001-11-27 — — US disclosed
EP-1050531-A1 Pyridine and piperidine derivatives for treating neurodegenerative diseases ADIR ET COMPAGNIE (FR) 2000-11-08 — — EP disclosed
EP-1050531-A1 Pyridine and piperidine derivatives for treating neurodegenerative diseases ADIR ET COMPAGNIE (FR) 2000-11-08 — — EP disclosed
US-4845228-A INTERMEDIATES FOR CARDIOTONIC AGENTS MITSUI TOATSU CHEMICALS, INC. (JP) 1989-07-04 — — US disclosed
US-4782154-A CARDIOTONICS MITSUI TOATSU CHEMICALS, INC. (JP) 1988-11-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030181484-A1 New substituted pyridine or piperidine compounds CNR1, HRH4, OPRD1 ALDH1A1 819/4885KDM4E 1888/4885DDB1 3970/4885
US-20240158340-A1 PHOTOCATALYTIC ARYLATION OF CARBONYL COMPOUNDS AND METHODS FOR USING THE SAME AHR, CBR3, AADAC ALDH1A1 319/4885KDM4E 1512/4885DDB1 4218/4885
US-20030139408-A1 Substituted pyridine or piperidine compounds P2RY1, HRH3, CNR1 ALDH1A1 551/4885KDM4E 1656/4885DDB1 3806/4885
US-20020035123-A1 New substituted pyridine or piperidine compounds OPRD1, CNR1, HRH4 ALDH1A1 878/4885KDM4E 1930/4885DDB1 3949/4885
US-20020040036-A1 New substituted pyridine or piperidine compounds CNR1, OPRD1, OPRK1 ALDH1A1 758/4885KDM4E 2121/4885DDB1 3874/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.