Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A2 | P43004 | 3/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.39 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.39 |
| ▸ | METAP1 | P53582 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 3/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16171989 | 0.82 | SLC1A3 (0.35) | SLC1A2SLC1A1SLC1A3TP53SLC15A1 | |
| SCHEMBL16240651 | 0.79 | DPP4 (0.54) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL16240652 | 0.79 | DPP4 (0.54) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL11342489 | 0.77 | SLC1A2 (0.42) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL8207593 | 0.77 | SLC1A2 (0.42) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL18774973 | 0.76 | SLC7A5 (0.54) | SLC1A2SLC1A1SLC1A3DPP4DPP9 | |
| Hydrochloric Acid SCHEMBL10925209 | 0.76 | ALDH1A1 (0.33) | SLC1A2SLC1A1SLC1A3ALDH1A1 | |
| SCHEMBL9366113 | 0.74 | BHMT (0.38) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL16240143 | 0.74 | BHMT (0.38) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL31754346 | 0.74 | SLC1A2 (0.39) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140308304-A1 | LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS | ALNYLAM PHARMACEUTICALS, INC. | 2014-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140308304-A1 | LIPIDS FOR THE DELIVERY OF ACTIVE AGENTS | NPC1L1, NPC1, CETP | SLC1A2 3240/4885SLC1A1 2306/4885SLC1A3 2141/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.