SCHEMBL16174656

SCHEMBL16174656

C=C(C#N)C(=O)OCCOCCOCCOCCO

nearest known ligand 0.53

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.53
ALDH1A1 P00352 3/20 0.53
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
THRB P10828 2/20 0.39
MAPK1 P28482 1/20 0.37
TP53 P04637 2/20 0.35
HIF1A Q16665 2/20 0.35
HSD17B10 Q99714 1/20 0.35
HTT P42858 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24506175 1.00 TSHR (0.53) TSHRALDH1A1MEN1KMT2ATHRB
SCHEMBL11802503 1.00 TSHR (0.53) TSHRALDH1A1MEN1KMT2ATHRB
SCHEMBL3786036 0.92 TSHR (0.61) TSHRALDH1A1THRBTP53HIF1A
SCHEMBL16290353 0.92 TSHR (0.61) TSHRALDH1A1THRBTP53HIF1A
SCHEMBL3791084 0.92 TSHR (0.61) TSHRALDH1A1THRBTP53HIF1A
SCHEMBL6288807 0.88 TSHR (0.61) TSHRALDH1A1THRB
SCHEMBL11393847 0.88 ALDH1A1 (0.73) TSHRALDH1A1MEN1KMT2ATHRB
Ethylene SCHEMBL8420922 0.86 TSHR (0.59) TSHRALDH1A1THRB
SCHEMBL4579700 0.86 TSHR (0.68) TSHRALDH1A1THRBTP53HIF1A
SCHEMBL24506037 0.84 TSHR (0.56) TSHRALDH1A1THRBTP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140369952-A1 BIODEGRADABLE MEDICAL ADHESIVE AND PREPARATION METHOD AND USE THEREOF CHENGDU YIPING MEDICAL SCIENCE & TECHNOLOGY CO., LTD. (CN) 2014-12-18 US claimed
EP-2792372-A1 BIODEGRADABLE MEDICAL ADHESIVE AND PREPARATION METHOD AND USE THEREOF Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China (CN) 2014-10-22 EP claimed
EP-2792372-B1 BIODEGRADABLE MEDICAL ADHESIVE AND PREPARATION METHOD AND USE THEREOF INST PHARMACOLOGY & TOXICOLOGY ACADEMY MILITARY MEDICAL SCIENCES PLA CHINA (CN) 2018-07-25 EP disclosed
US-9750841-B2 Biodegradable medical adhesive and preparation method and use thereof INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY ACADEMY OF MILITARY MEDICAL SCIENCES P.L.A. (CN) 2017-09-05 US disclosed
US-20140369952-A1 BIODEGRADABLE MEDICAL ADHESIVE AND PREPARATION METHOD AND USE THEREOF CHENGDU YIPING MEDICAL SCIENCE & TECHNOLOGY CO., LTD. (CN) 2014-12-18 US disclosed
EP-2792372-A1 BIODEGRADABLE MEDICAL ADHESIVE AND PREPARATION METHOD AND USE THEREOF Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. China (CN) 2014-10-22 EP disclosed