Ethylene

Ethylene

SCHEMBL8420922

C=C.C=C(C#N)C(=O)OCCO

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.59
ALDH1A1 P00352 1/20 0.59
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6288807 0.98 TSHR (0.61) TSHRALDH1A1THRB
SCHEMBL4579700 0.87 TSHR (0.68) TSHRALDH1A1THRB
SCHEMBL24506175 0.86 TSHR (0.53) TSHRALDH1A1THRB
SCHEMBL11802503 0.86 TSHR (0.53) TSHRALDH1A1THRB
SCHEMBL16174656 0.86 TSHR (0.53) TSHRALDH1A1THRB
SCHEMBL11799311 0.86 TSHR (0.57) TSHRALDH1A1
SCHEMBL27907823 0.84 TSHR (0.55) TSHRALDH1A1
SCHEMBL5404500 0.83 ALDH1A1 (0.59) TSHRALDH1A1THRB
SCHEMBL4578754 0.83 TSHR (0.63) TSHRALDH1A1THRB
SCHEMBL4580407 0.83 TSHR (0.63) TSHRALDH1A1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100586479-C Application of cyanoacrylate glycol ester in preparing medicine carrier INST BIOMEDICAL ENG CAMS 2010-02-03 CN disclosed
CN-101284131-A Application of cyanoacrylate glycol ester in preparing medicine carrier INST BIOMEDICAL ENG CAMS (CN) 2008-10-15 CN disclosed
US-6001958-A POLYMER HAS ON AT LEAST TWO OF ITS ENDS, AT LEAST ONE REACTIVE END GROUP OF A DIFFERENT CHEMICAL TYPE FROM THAT OF THE GROUP PREDOMINANTLY USED IN POLYMERIZATION AND THE PREPARATION OF A POLYMER SKELETON. FLAMEL TECHNOLOGIES (FR) 1999-12-14 US disclosed