Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | ESR1 | P03372 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6098839 | 0.88 | TDP1 (0.57) | TDP1ALDH1A1LMNACES2CES1 | |
| SCHEMBL8995839 | 0.86 | TDP1 (0.52) | TDP1ALDH1A1LMNACES2CES1 | |
| SCHEMBL31176004 | 0.86 | TDP1 (0.55) | TDP1ALDH1A1LMNACES2CES1 | |
| SCHEMBL6654554 | 0.84 | TDP1 (0.70) | TDP1ALDH1A1LMNACES2CES1 | |
| SCHEMBL248492 | 0.84 | TDP1 (0.70) | TDP1ALDH1A1LMNACES2CES1 | |
| SCHEMBL28646948 | 0.84 | TDP1 (0.53) | TDP1ALDH1A1LMNACES2CES1 | |
| SCHEMBL8371274 | 0.84 | TDP1 (0.53) | TDP1ALDH1A1LMNACES2CES1 | |
| SCHEMBL775876 | 0.84 | TDP1 (0.53) | TDP1ALDH1A1LMNACES2CES1 | |
| SCHEMBL6655202 | 0.83 | ESR1 (0.62) | TDP1ALDH1A1LMNAKMT2AMAPT | |
| SCHEMBL27818338 | 0.82 | L3MBTL1 (0.47) | TDP1ALDH1A1LMNAKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108430989-B | Process for preparing 1, 4-dihydropyridine-3, 5-dicarboxylate derivatives and intermediates | 轩竹生物科技有限公司 | 2021-10-08 | — | — | CN | disclosed |
| US-9150723-B2 | Curable resin composition | THREE BOND FINE CHEMICAL CO., LTD. (JP) | 2015-10-06 | — | — | US | disclosed |
| US-20150239864-A1 | 3H-1,2-DITHIOCYCLOPENTENE-3-THIOKETONE COMPOUNDS AND APPLICATION THEREOF | SOOCHOW UNIVERSITY (CN) | 2015-08-27 | — | — | US | disclosed |
| EP-2889294-A1 | 3H-1,2-DITHIOCYCLOPENTENE-3-THIOKETONE COMPOUNDS AND APPLICATION THEREOF | Soochow University (CN) | 2015-07-01 | — | — | EP | disclosed |
| US-20140329926-A1 | CURABLE RESIN COMPOSITION | THREE BOND FINE CHEMICAL CO., LTD (JP) | 2014-11-06 | — | — | US | disclosed |
| EP-2792694-A1 | CURABLE RESIN COMPOSITION | Three Bond Fine Chemical Co., Ltd. (JP) | 2014-10-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150239864-A1 | 3H-1,2-DITHIOCYCLOPENTENE-3-THIOKETONE COMPOUNDS AND APPLICATION THEREOF | TXN2, TXN, TXNRD2 | TDP1 445/4885ALDH1A1 370/4885LMNA 3765/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.