Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | LTA4H | P09960 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19189977 | 0.92 | RAB9A (0.60) | RAB9AALDH1A1MEN1KMT2ACYP2D6 | |
| SCHEMBL17967832 | 0.88 | KDM4E (0.58) | RAB9AALDH1A1MEN1KMT2ACYP2D6 | |
| SCHEMBL23775702 | 0.87 | MEN1 (0.57) | RAB9AALDH1A1MEN1KMT2ACYP2D6 | |
| SCHEMBL23775592 | 0.85 | RAB9A (0.58) | RAB9AALDH1A1MEN1KMT2ACYP2D6 | |
| SCHEMBL15033035 | 0.83 | HRH3 (0.71) | RAB9AALDH1A1MEN1KMT2ACYP2D6 | |
| SCHEMBL8791728 | 0.82 | HRH3 (0.71) | RAB9AALDH1A1MEN1KMT2ACYP2D6 | |
| SCHEMBL15071697 | 0.82 | HRH3 (0.53) | RAB9AALDH1A1MEN1KMT2ACYP2D6 | |
| SCHEMBL8791487 | 0.82 | RAB9A (0.61) | RAB9AALDH1A1MEN1KMT2ACYP2D6 | |
| SCHEMBL5175342 | 0.82 | LTA4H (0.61) | RAB9ANPC1HRH3LTA4H | |
| SCHEMBL1586714 | 0.81 | SIGMAR1 (0.63) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014167371-A1 | ANALOGS OF THE ANTIBIOTIC AMINOTHIAZOLE GE2270 | NAICONS S.C.A.R.L. (IT) | 2014-10-16 | — | — | WO | disclosed |