SCHEMBL161773

SCHEMBL161773

CC1O[C@@H](Oc2c(-c3ccc(O)cc3)oc3cc(O)cc(O)c3c2=O)[C@@H](OC(=O)/C=C/c2ccc(O)cc2)C(OC(=O)/C=C/c2ccc(O)cc2)[C@H]1O

nearest known ligand 0.88

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CBS P35520 1/20 0.88
CYP3A4 P08684 9/20 0.78
CA12 O43570 3/20 0.73
CA4 P22748 3/20 0.73
CA7 P43166 3/20 0.73
CA2 P00918 2/20 0.73
RPS6KA3 P51812 7/20 0.68
CYP2D6 P10635 2/20 0.68
RPS6KA1 Q15418 1/20 0.68
NQO2 P16083 1/20 0.67
TYR P14679 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24464006 1.00 CBS (0.88) CBSCYP3A4CA12CA4CA7
SCHEMBL24464005 1.00 CBS (0.88) CBSCYP3A4CA12CA4CA7
SCHEMBL29753914 1.00 CBS (0.88) CBSCYP3A4CA12CA4CA7
SCHEMBL16131011 0.94 CBS (1.00) CBSCYP3A4CA12CA4CA7
SCHEMBL13973879 0.94 CBS (1.00) CBSCYP3A4CA12CA4CA7
SCHEMBL13963385 0.94 CBS (1.00) CBSCYP3A4CA12CA4CA7
SCHEMBL29380642 0.91 CYP3A4 (0.83) CBSCYP3A4CA12CA4CA7
SCHEMBL572336 0.88 CYP3A4 (1.00) CBSCYP3A4RPS6KA3CYP2D6RPS6KA1
SCHEMBL30445487 0.86 CA12 (0.81) CBSCYP3A4CA12CA4CA7
SCHEMBL31402522 0.86 CA12 (0.86) CBSCYP3A4CA12CA4CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3894400-B1 COMPOSITIONS COMPRISING PLATANOSIDE AND ISOMERS THEREOF FOR USE IN THE TREATEMENT OF PANCREATIC, LIVER OR BRAIN CANCER SHARE GAL RES AND DEVELOPMENT LTD (IL) 2024-09-11 EP claimed
US-11344567-B2 Methods of treating cancer using platanoside and isomers thereof SHARE GAL RESEARCH AND DEVELOPMENT LTD (IL) 2022-05-31 US claimed
US-20220040213-A1 METHODS OF TREATING CANCER USING PLATANOSIDE AND ISOMERS THEREOF SHARE GAL RESEARCH AND DEVELOPMENT LTD (IL) 2022-02-10 US claimed
EP-3894400-A1 METHODS OF TREATING CANCER USING PLATANOSIDE AND ISOMERS THEREOF Share Gal Research And Development Ltd (IL) 2021-10-20 EP claimed
WO-2020121297-A1 METHODS OF TREATING CANCER USING PLATANOSIDE AND ISOMERS THEREOF SHARE GAL RESEARCH AND DEVELOPMENT LTD (IL) 2020-06-18 WO claimed
EP-3894400-C0 COMPOSITIONS COMPRISING PLATANOSIDE AND ISOMERS THEREOF FOR USE IN THE TREATEMENT OF PANCREATIC, LIVER OR BRAIN CANCER SHARE GAL RES AND DEVELOPMENT LTD (IL) 2024-09-11 EP disclosed
EP-3894400-B1 COMPOSITIONS COMPRISING PLATANOSIDE AND ISOMERS THEREOF FOR USE IN THE TREATEMENT OF PANCREATIC, LIVER OR BRAIN CANCER SHARE GAL RES AND DEVELOPMENT LTD (IL) 2024-09-11 EP disclosed
EP-3894400-B1 COMPOSITIONS COMPRISING PLATANOSIDE AND ISOMERS THEREOF FOR USE IN THE TREATEMENT OF PANCREATIC, LIVER OR BRAIN CANCER SHARE GAL RES AND DEVELOPMENT LTD (IL) 2024-09-11 EP disclosed
EP-3894400-A4 METHODS OF TREATING CANCER USING PLATANOSIDE AND ISOMERS THEREOF Share Gal Research And Development Ltd (IL) 2022-07-27 EP disclosed
US-11344567-B2 Methods of treating cancer using platanoside and isomers thereof SHARE GAL RESEARCH AND DEVELOPMENT LTD (IL) 2022-05-31 US disclosed
US-11344567-B2 Methods of treating cancer using platanoside and isomers thereof SHARE GAL RESEARCH AND DEVELOPMENT LTD (IL) 2022-05-31 US disclosed
US-11344567-B2 Methods of treating cancer using platanoside and isomers thereof SHARE GAL RESEARCH AND DEVELOPMENT LTD (IL) 2022-05-31 US disclosed
US-8801924-B2 Chromatography methods IRONSTONE SEPARATIONS, INC. (US) 2014-08-12 US disclosed
US-8633166-B2 Methicillin-resistant Staphylococcus aureus active metabolites HAMANN, MARK T. 2014-01-21 US disclosed
US-20130199999-A1 Chromatography Methods IRONSTONE SEPARATIONS, INC. (US) 2013-08-08 US disclosed
EP-2590722-A1 CHROMATOGRAPHY METHODS Ironstone Separations, Inc. (US) 2013-05-15 EP disclosed
WO-2012030432-A1 CHROMATOGRAPHY METHODS IRONSTONE SEPARATIONS, INC. (US) 2012-03-08 WO disclosed
US-20100273726-A1 METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS ACTIVE METABOLITES ISOLATED FROM LAURUS NOBILIS AND COMBINATIONS THEREOF TRITON BIOPHARMA (US) 2010-10-28 US disclosed
WO-2010107793-A1 METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS ACTIVE METABOLITES THE UNIVERSITY OF MISSISSIPPI (US) 2010-09-23 WO disclosed
US-20100234311-A1 Methicillin-Resistant Staphylococcus Aureus Active Metabolites THE UNIVERSITY OF MISSISSIPPI (US) 2010-09-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220040213-A1 METHODS OF TREATING CANCER USING PLATANOSIDE AND ISOMERS THEREOF EPHB3, EPHB1, FOLR1 CBS 2108/4885CYP3A4 238/4885CA12 799/4885
US-20100273726-A1 METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS ACTIVE METABOLITES ISOLATED FROM LAURUS NOBILIS AND COMBINATIONS THEREOF MRPS18A, CD14, MRPL38 CBS 4674/4885CYP3A4 3662/4885CA12 4493/4885
US-11344567-B2 Methods of treating cancer using platanoside and isomers thereof EPHB3, EPHB1, FOLR1 CBS 2108/4885CYP3A4 238/4885CA12 799/4885
US-20100234311-A1 Methicillin-Resistant Staphylococcus Aureus Active Metabolites HM13, FOS, MRPS23 CBS 4757/4885CYP3A4 4387/4885CA12 4640/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.