Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | BMP1 | P13497 | 2/20 | 0.38 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SCN1A | P35498 | 1/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16757195 | 0.92 | SOS1 (0.38) | ALOX12MEN1KMT2ATAS2R14TP53 | |
| SCHEMBL29668838 | 0.90 | KEAP1 (0.41) | ALOX12MEN1KMT2ATAS2R14TP53 | |
| SCHEMBL17048628 | 0.90 | KEAP1 (0.41) | ALOX12MEN1KMT2ATAS2R14TP53 | |
| SCHEMBL16771674 | 0.90 | GAA (0.41) | ALOX12MEN1KMT2ATAS2R14TP53 | |
| SCHEMBL322898 | 0.89 | SLC22A12 (0.42) | ALOX12MEN1KMT2ASCN9A | |
| SCHEMBL3123476 | 0.89 | MEN1 (0.41) | ALOX12MEN1KMT2ATAS2R14NPC1 | |
| SCHEMBL29669070 | 0.88 | MEN1 (0.40) | ALOX12MEN1KMT2ATP53SCN1A | |
| SCHEMBL15466024 | 0.88 | MEN1 (0.40) | ALOX12MEN1KMT2ATP53SCN1A | |
| SCHEMBL20485792 | 0.87 | CNR2 (0.43) | ALOX12MEN1KMT2ATP53GAA | |
| SCHEMBL29668807 | 0.86 | KDM4E (0.42) | ALOX12MEN1KMT2ATP53SCN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014170793-A1 | SULFONAMIDES FOR THE TREATMENT OF GOUT | PFIZER LIMITED (GB) | 2014-10-23 | — | — | WO | disclosed |
| US-20140315933-A1 | CHEMICAL COMPOUNDS | PFIZER LIMITED (GB) | 2014-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140315933-A1 | CHEMICAL COMPOUNDS | SULT2A1, SULT1A1, SULT1E1 | ALOX12 4209/4885MEN1 3205/4885KMT2A 1586/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.