Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | PPARG | P37231 | 3/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | RXRA | P19793 | 2/20 | 0.35 |
| ▸ | OXER1 | Q8TDS5 | 2/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | F7 | P08709 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | F3 | P13726 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16178260 | 1.00 | TAS1R3 (0.44) | TAS1R3TAS1R1PPARAALDH1A1PPARG | |
| SCHEMBL2128303 | 0.92 | TAS1R3 (0.48) | TAS1R3TAS1R1PPARAALDH1A1PPARG | |
| SCHEMBL9069564 | 0.92 | TAS1R3 (0.48) | TAS1R3TAS1R1PPARAALDH1A1PPARG | |
| SCHEMBL182648 | 0.87 | ALDH1A1 (0.39) | PPARAALDH1A1PPARGCYP19A1RXRA | |
| SCHEMBL9593302 | 0.87 | ALDH1A1 (0.39) | PPARAALDH1A1PPARGCYP19A1RXRA | |
| SCHEMBL16181330 | 0.87 | ALDH1A1 (0.39) | PPARAALDH1A1PPARGCYP19A1RXRA | |
| Benzene SCHEMBL27686539 | 0.85 | TAS1R3 (0.44) | TAS1R3TAS1R1PPARAALDH1A1PPARG | |
| (2E)-Hexenoic Acid SCHEMBL28057315 | 0.85 | PPARA (0.48) | TAS1R3TAS1R1PPARAALDH1A1PPARG | |
| SCHEMBL25397513 | 0.84 | PPARG (0.50) | PPARAPPARGCYP19A1MAPTPTPN1 | |
| SCHEMBL20140196 | 0.82 | PPARG (0.53) | PPARAPPARGCYP19A1MAPTPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10131873-B2 | Cell culture compositions with antioxidants and methods for polypeptide production | GENENTECH, INC. (US) | 2018-11-20 | — | — | US | disclosed |
| US-10017732-B2 | Cell culture compositions with antioxidants and methods for polypeptide production | GENENTECH, INC. (US) | 2018-07-10 | — | — | US | disclosed |
| US-20160002593-A1 | CELL CULTURE COMPOSITIONS WITH ANTIOXIDANTS AND METHODS FOR POLYPEPTIDE PRODUCTION | GENENTECH, INC. (US) | 2016-01-07 | — | — | US | disclosed |
| US-20140314779-A1 | CELL CULTURE COMPOSITIONS WITH ANTIOXIDANTS AND METHODS FOR POLYPEPTIDE PRODUCTION | GENENTECH, INC. (US) | 2014-10-23 | — | — | US | disclosed |