Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 8/20 | 0.54 |
| ▸ | USP25 | Q9UHP3 | 2/20 | 0.45 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.45 |
| ▸ | ESRRB | O95718 | 2/20 | 0.42 |
| ▸ | ESRRG | P62508 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | WEE1 | P30291 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | HTR5A | P47898 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | CDK4 | P11802 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24028130 | 0.86 | ADRB1 (0.46) | ADRB1USP25USP28ESRRBESRRG | |
| SCHEMBL29104004 | 0.84 | ADRB1 (0.45) | ADRB1USP25USP28ESRRBESRRG | |
| SCHEMBL21876742 | 0.84 | LTA4H (0.46) | ADRB1USP25USP28SUV39H2ADRA2A | |
| SCHEMBL29104008 | 0.84 | ADRB1 (0.45) | ADRB1USP25USP28ESRRBESRRG | |
| SCHEMBL29104071 | 0.84 | ADRB1 (0.45) | ADRB1USP25USP28ESRRBESRRG | |
| SCHEMBL21876740 | 0.84 | LTA4H (0.46) | ADRB1USP25USP28SUV39H2ADRA2A | |
| SCHEMBL6907009 | 0.84 | ADRB1 (0.60) | ADRB1USP25USP28KCNH2ADRA2A | |
| SCHEMBL6907013 | 0.84 | ADRB1 (0.60) | ADRB1USP25USP28KCNH2ADRA2A | |
| SCHEMBL20883649 | 0.84 | ADRB1 (0.42) | ADRB1USP25USP28SUV39H2ADRA2A | |
| SCHEMBL22542075 | 0.82 | ADRB1 (0.47) | ADRB1USP25USP28WEE1HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020210377-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | NUVATION BIO INC. (US) | 2020-10-15 | — | — | WO | disclosed |
| WO-2020210383-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | NUVATION BIO INC. (US) | 2020-10-15 | — | — | WO | disclosed |
| US-9096614-B2 | Therapeutically active thiazolo-pyrimidine derivatives | UCB PHARMA SA (BE) | 2015-08-04 | — | — | US | disclosed |
| US-20140315885-A1 | Therapeutically Active Thiazolo-Pyrimidine Derivatives | UCB PHARMA SA (BE) | 2014-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140315885-A1 | Therapeutically Active Thiazolo-Pyrimidine Derivatives | TPMT, IFNG, IRF3 | ADRB1 1401/4885USP25 4395/4885USP28 4190/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.