Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HB | P07237 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16463712 | 0.83 | ALDH1A1 (0.63) | P4HBPOLBALDH1A1L3MBTL1MAPT | |
| SCHEMBL16179288 | 0.81 | HPGD (0.48) | ALDH1A1L3MBTL1MAPTHPGDHTT | |
| SCHEMBL11156973 | 0.80 | CHRM2 (0.59) | P4HBPOLBALDH1A1L3MBTL1MAPT | |
| SCHEMBL17240261 | 0.79 | CYP1A2 (0.46) | ALDH1A1MEN1KMT2A | |
| SCHEMBL7205156 | 0.79 | P4HB (0.46) | P4HBPOLBALDH1A1L3MBTL1MAPT | |
| SCHEMBL24369695 | 0.78 | CHRM2 (0.57) | P4HBPOLBALDH1A1MAPTSMAD3 | |
| SCHEMBL20851520 | 0.78 | CHRM2 (0.57) | P4HBPOLBALDH1A1MAPTSMAD3 | |
| SCHEMBL19397162 | 0.78 | CHRM2 (0.57) | P4HBPOLBALDH1A1MAPTSMAD3 | |
| SCHEMBL27552081 | 0.76 | ALDH1A1 (0.47) | P4HBPOLBALDH1A1L3MBTL1MAPT | |
| SCHEMBL9534090 | 0.76 | CYP2D6 (0.43) | ALDH1A1L3MBTL1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014170343-A1 | DEPOLARIZING AGENTS AND NICOTINIC ACETYLCHOLINE RECEPTOR MODULATORS FOR TREATING DOPAMINERGIC-RELATED DISORDERS | ICM (INSTITUT DU CERVEAU ET DE LA MOELLE ÉPINIÈRE) (FR) | 2014-10-23 | — | — | WO | disclosed |