Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 4/20 | 0.57 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.57 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.55 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | P4HB | P07237 | 2/20 | 0.46 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20851520 | 1.00 | CHRM2 (0.57) | CHRM2CHRM1CHRM4CHRM3ACHE | |
| SCHEMBL24369695 | 1.00 | CHRM2 (0.57) | CHRM2CHRM1CHRM4CHRM3ACHE | |
| SCHEMBL11156973 | 0.98 | CHRM2 (0.59) | CHRM2CHRM1CHRM4CHRM3ACHE | |
| SCHEMBL2091674 | 0.85 | CHRM2 (0.49) | CHRM2CHRM1CHRM4CHRM3ACHE | |
| SCHEMBL8983621 | 0.84 | ALDH1A1 (0.65) | CHRM2CHRM1CHRM4CHRM3ACHE | |
| SCHEMBL16026527 | 0.84 | ADRB1 (0.54) | CHRM2CHRM1CHRM4CHRM3CYP2D6 | |
| SCHEMBL3709025 | 0.84 | HSD11B1 (0.56) | CHRM2CHRM1CHRM4CHRM3ACHE | |
| SCHEMBL12444346 | 0.81 | CHRM2 (0.52) | CHRM2CHRM1CHRM4CHRM3ACHE | |
| SCHEMBL16982012 | 0.79 | CYP2D6 (0.56) | CHRM2CHRM1CYP2D6MEN1KMT2A | |
| SCHEMBL27889529 | 0.79 | CYP2D6 (0.43) | CHRM2CHRM1CHRM4CHRM3ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112441888-B | Pd-ReOx/CeO2Method for preparing nitrogen-containing aromatic compound by catalyzing lignin ammoniation reaction | 中国科学院大连化学物理研究所 | 2021-10-26 | — | — | CN | claimed |
| CN-112441888-A | Pd-ReOx/CeO2Method for preparing nitrogen-containing aromatic compound by catalyzing lignin ammoniation reaction | 中国科学院大连化学物理研究所 | 2021-03-05 | — | — | CN | claimed |
| EP-4232425-A1 | CTPS1 INHIBITORS AND USES THEREOF | Nimbus Clotho, Inc. (US) | 2023-08-30 | — | — | EP | disclosed |
| WO-2022087634-A1 | CTPS1 INHIBITORS AND USES THEREOF | NIMBUS CLOTHO, INC. (US) | 2022-04-28 | — | — | WO | disclosed |
| CN-112441888-B | Pd-ReOx/CeO2Method for preparing nitrogen-containing aromatic compound by catalyzing lignin ammoniation reaction | 中国科学院大连化学物理研究所 | 2021-10-26 | — | — | CN | disclosed |
| CN-112441888-A | Pd-ReOx/CeO2Method for preparing nitrogen-containing aromatic compound by catalyzing lignin ammoniation reaction | 中国科学院大连化学物理研究所 | 2021-03-05 | — | — | CN | disclosed |
| US-9962388-B2 | Pyrrolopyrimidine compounds used as TLR7 agonist | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) | 2018-05-08 | — | — | US | disclosed |
| US-20170273983-A1 | PYRROLOPYRIMIDINE COMPOUNDS USED AS TLR7 AGONIST | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) | 2017-09-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170273983-A1 | PYRROLOPYRIMIDINE COMPOUNDS USED AS TLR7 AGONIST | TLR7, TLR9, TLR1 | CHRM2 4357/4885CHRM1 3839/4885CHRM4 2756/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.