Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 3/20 | 0.41 |
| ▸ | DYRK2 | Q92630 | 3/20 | 0.41 |
| ▸ | DYRK1B | Q9Y463 | 3/20 | 0.41 |
| ▸ | DYRK3 | O43781 | 2/20 | 0.41 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.41 |
| ▸ | CDK9 | P50750 | 2/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.41 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.41 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.41 |
| ▸ | AXL | P30530 | 1/20 | 0.41 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | FNTA | P49354 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1940329 | 0.79 | PTGDR2 (0.49) | PTGDR2CLK4CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL16180553 | 0.79 | KDM1A (0.44) | TRIM24TRIM33PTGDR2CA12CA1 | |
| SCHEMBL2554294 | 0.77 | TRIM24 (0.60) | DYRK1ADYRK2DYRK1BDYRK3CCNT1 | |
| SCHEMBL6061092 | 0.76 | KDM1A (0.44) | DYRK1ADYRK2DYRK1BDYRK3CCNT1 | |
| SCHEMBL16180558 | 0.74 | CYP11B1 (0.49) | TRIM24TRIM33CDK8CA12CA1 | |
| SCHEMBL16180046 | 0.73 | KDM1A (0.47) | PTGDR2FNTAFNTBTSHRP4HB | |
| SCHEMBL15821011 | 0.73 | TRIM24 (0.49) | TRIM24TRIM33CLK4CA12CA1 | |
| SCHEMBL16180126 | 0.72 | GABRG2 (0.49) | DYRK1ADYRK2DYRK1BDYRK3CCNT1 | |
| SCHEMBL6509365 | 0.71 | TRIM24 (0.56) | TRIM24TRIM33CDK8BRD4CA12 | |
| SCHEMBL6062294 | 0.70 | EGLN2 (0.41) | TRIM24TRIM33AXLBRD4CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2986607-B1 | ANTIBACTERIAL BIAROMATIC DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2017-06-14 | — | — | EP | disclosed |
| US-9527867-B2 | Antibacterial biaromatic derivatives | ACTELION PHARMACEUTICALS LTD. (CH) | 2016-12-27 | — | — | US | disclosed |
| US-20160075722-A1 | Antibacterial Biaromatic Derivatives | IDORSIA PHARMACEUTICALS LTD (CH) | 2016-03-17 | — | — | US | disclosed |
| EP-2986607-A1 | ANTIBACTERIAL BIAROMATIC DERIVATIVES | Actelion Pharmaceuticals Ltd. (CH) | 2016-02-24 | — | — | EP | disclosed |
| WO-2014170821-A1 | ANTIBACTERIAL BIAROMATIC DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2014-10-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160075722-A1 | Antibacterial Biaromatic Derivatives | CYC1, C5, CYCS | DYRK1A 3620/4885DYRK2 3835/4885DYRK1B 3332/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.