Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13970602 | 1.00 | HTR2C (0.36) | HTR2CHTR2AHTR2BTAAR1MAOA | |
| SCHEMBL13970601 | 1.00 | HTR2C (0.36) | HTR2CHTR2AHTR2BTAAR1MAOA | |
| SCHEMBL13950182 | 0.81 | HTR2C (0.34) | HTR2CHTR2AHTR2BTAAR1DDB1 | |
| SCHEMBL13950194 | 0.81 | HTR2C (0.34) | HTR2CHTR2AHTR2BTAAR1DDB1 | |
| SCHEMBL13950181 | 0.81 | HTR2C (0.34) | HTR2CHTR2AHTR2BTAAR1DDB1 | |
| SCHEMBL13394484 | 0.76 | ALOX5 (0.38) | HTR2CHTR2AHTR2BTAAR1DDB1 | |
| SCHEMBL16181048 | 0.74 | HSD11B1 (0.40) | HTR2CHTR2AHTR2BTAAR1DDB1 | |
| SCHEMBL19254483 | 0.70 | MEN1 (0.39) | MAOADDB1CRBNGAAMAOB | |
| SCHEMBL15927658 | 0.70 | HTR2B (0.43) | HTR2CHTR2AHTR2BTAAR1DDB1 | |
| SCHEMBL16181049 | 0.68 | TTR (0.37) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8865707-B2 | Cholesteryl ester transfer protein inhibitors | MERCK SHARP & DOHME CORP. (US) | 2014-10-21 | — | — | US | disclosed |