SCHEMBL19254483

SCHEMBL19254483

Cc1ccccc1C1OC(=O)N(C)C1O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
ATM Q13315 1/20 0.39
GAA P10253 1/20 0.38
TSHR P16473 1/20 0.38
MAOB P27338 5/20 0.35
MAOA P21397 3/20 0.35
HDAC4 P56524 1/20 0.35
AOC1 P19801 2/20 0.35
PBRM1 Q86U86 1/20 0.34
TNKS2 Q9H2K2 1/20 0.34
MAPT P10636 2/20 0.34
ALDH1A1 P00352 1/20 0.34
HPGD P15428 1/20 0.34
USP2 O75604 1/20 0.34
THRB P10828 1/20 0.34
TERT O14746 1/20 0.33
DDB1 Q16531 1/20 0.33
CRBN Q96SW2 1/20 0.33
CA12 O43570 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15083026 0.82 KDM4E (0.43) KMT2AGAATSHRMAOBMAOA
SCHEMBL3435945 0.82 KDM4E (0.43) KMT2AGAATSHRMAOBMAOA
SCHEMBL15088593 0.78 ALDH1A1 (0.30) ALDH1A1
SCHEMBL23347646 0.77 CYSLTR2 (0.34) MAOAALDH1A1
SCHEMBL13970602 0.70 HTR2C (0.36) MEN1KMT2AGAATSHRMAOB
SCHEMBL13970601 0.70 HTR2C (0.36) MEN1KMT2AGAATSHRMAOB
SCHEMBL11356776 0.66 PBRM1 (0.42) MEN1KMT2APBRM1TNKS2ALDH1A1
SCHEMBL16181048 0.65 HSD11B1 (0.40) DDB1CRBN
SCHEMBL47323 0.64
SCHEMBL5598888 0.63 MAOB (0.47) MEN1KMT2AGAATSHRMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2797878-B1 PHENYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING STROKE BIO-PHARM SOLUTIONS CO LTD (KR) 2017-08-16 EP disclosed