Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 7/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | BRD4 | O60885 | 2/20 | 0.43 |
| ▸ | BRD2 | P25440 | 2/20 | 0.43 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | PDE2A | O00408 | 1/20 | 0.43 |
| ▸ | PIK3C2A | O00443 | 1/20 | 0.43 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.43 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.43 |
| ▸ | PDE5A | O76074 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL430105 | 0.98 | PRKDC (0.46) | PRKDCALOX5ALDH1A1PIK3CDPIK3CA | |
| SCHEMBL429325 | 0.98 | PRKDC (0.49) | PRKDCALOX5ALDH1A1PIK3CDPIK3CA | |
| SCHEMBL429313 | 0.94 | ALOX5 (0.46) | PRKDCALOX5ALDH1A1PIK3CDPIK3CA | |
| SCHEMBL11713826 | 0.94 | PRKDC (0.47) | PRKDCALOX5ALDH1A1PIK3CDPIK3CA | |
| SCHEMBL22151549 | 0.89 | ALOX5 (0.49) | PRKDCALOX5ALDH1A1PIK3CDPIK3CA | |
| SCHEMBL21425280 | 0.88 | GPR55 (0.44) | PRKDCALOX5ALDH1A1PIK3CDPIK3CA | |
| SCHEMBL23975325 | 0.87 | GPR55 (0.42) | PRKDCALOX5ALDH1A1PIK3CDPIK3CA | |
| SCHEMBL17057246 | 0.87 | ALOX5 (0.46) | PRKDCALOX5ALDH1A1PIK3CDPIK3CA | |
| SCHEMBL21157074 | 0.86 | PRKDC (0.45) | PRKDCALOX5ALDH1A1PIK3CDPIK3CA | |
| SCHEMBL21431853 | 0.86 | ALOX5 (0.59) | PRKDCALOX5ALDH1A1PIK3CDPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2428512-B1 | Fluorene compound, light-emitting element, light-emitting device, electronic device and lighting device | SEMICONDUCTOR ENERGY LAB (JP) | 2014-10-22 | — | — | EP | disclosed |