SCHEMBL21157074

SCHEMBL21157074

c1ccc(-c2cc(-c3ccccc3)cc(-c3ccccc3-c3ccccc3-c3cccc4c3oc3c(-c5ccccc5-c5ccccc5-c5cc(-c6ccccc6)cc(-c6ccccc6)c5)cccc34)c2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRKDC P78527 9/20 0.45
ALOX5 P09917 2/20 0.41
PLA2G2A P14555 3/20 0.38
PLA2G4A P47712 3/20 0.38
SMN1; SMN2 Q16637 4/20 0.38
ALDH1A1 P00352 3/20 0.38
PIK3CD O00329 3/20 0.38
PIK3CA P42336 3/20 0.38
PIK3CB P42338 3/20 0.38
PIK3CG P48736 3/20 0.38
KDM4E B2RXH2 2/20 0.38
BRD4 O60885 2/20 0.38
BRD2 P25440 2/20 0.38
BRD3 Q15059 2/20 0.38
TP53 P04637 2/20 0.38
CYP3A4 P08684 2/20 0.38
PDE2A O00408 1/20 0.38
PIK3C2A O00443 1/20 0.38
PIK3R2 O00459 1/20 0.38
PIK3C2B O00750 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21157813 1.00 PRKDC (0.45) PRKDCALOX5PLA2G2APLA2G4ASMN1; SMN2
SCHEMBL429314 0.89 PRKDC (0.50) PRKDCALOX5PLA2G2APLA2G4ASMN1; SMN2
SCHEMBL1635697 0.89 ALOX5 (0.44) PRKDCALOX5PLA2G2APLA2G4ASMN1; SMN2
SCHEMBL429325 0.88 PRKDC (0.49) PRKDCALOX5SMN1; SMN2ALDH1A1PIK3CD
SCHEMBL21157904 0.87 PRKDC (0.51) PRKDCALOX5PLA2G2APLA2G4ASMN1; SMN2
SCHEMBL22182837 0.87 ALOX5 (0.49) PRKDCALOX5PLA2G2APLA2G4ASMN1; SMN2
SCHEMBL16182124 0.86 PRKDC (0.48) PRKDCALOX5SMN1; SMN2ALDH1A1PIK3CD
SCHEMBL22182839 0.85 ALOX5 (0.47) PRKDCALOX5PLA2G2APLA2G4ASMN1; SMN2
SCHEMBL429313 0.85 ALOX5 (0.46) PRKDCALOX5PLA2G2APLA2G4ASMN1; SMN2
SCHEMBL430105 0.84 PRKDC (0.46) PRKDCALOX5SMN1; SMN2ALDH1A1PIK3CD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190214577-A1 THERMALLY ACTIVATED DELAYED FLUORESCENCE MATERIAL, POLYMER, MIXTURE, FORMULATION, AND ORGANIC ELECTRONIC DEVICE GUANGZHOU CHINARAY OPTOELECTRONIC MATERIALS LTD. (CN) 2019-07-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190214577-A1 THERMALLY ACTIVATED DELAYED FLUORESCENCE MATERIAL, POLYMER, MIXTURE, FORMULATION, AND ORGANIC ELECTRONIC DEVICE TEAD2, TEAD3, TEAD1 PRKDC 2062/4885ALOX5 3964/4885PLA2G2A 4699/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.