Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K2 | Q12851 | 2/20 | 0.51 |
| ▸ | ABCG2 | Q9UNQ0 | 9/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.48 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | PDE5A | O76074 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14473966 | 0.92 | ABCG2 (0.60) | MAP4K2ABCG2MEN1KMT2AKDM4E | |
| SCHEMBL2155854 | 0.83 | ABCG2 (0.60) | ABCG2MEN1KMT2AKDM4ELMNA | |
| SCHEMBL14474373 | 0.80 | MEN1 (0.48) | ABCG2MEN1KMT2AKDM4ELMNA | |
| SCHEMBL14473973 | 0.80 | MAPT (0.49) | ABCG2MEN1KMT2AKDM4ELMNA | |
| SCHEMBL14474752 | 0.80 | MEN1 (0.51) | ABCG2MEN1KMT2AKDM4ELMNA | |
| SCHEMBL14474768 | 0.80 | MAPT (0.48) | ABCG2MEN1KMT2AKDM4ELMNA | |
| SCHEMBL14727469 | 0.79 | ABCG2 (0.46) | ABCG2MEN1KMT2AKDM4ELMNA | |
| SCHEMBL16183301 | 0.79 | ABCG2 (0.60) | ABCG2MEN1KMT2AKDM4ELMNA | |
| SCHEMBL14358798 | 0.79 | ABCG2 (0.60) | ABCG2MEN1KMT2AKDM4ELMNA | |
| SCHEMBL16183244 | 0.79 | AURKA (0.60) | ABCG2MEN1KMT2AKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140315886-A1 | QUINAZOLINES AS THERAPEUTIC COMPOUNDS AND RELATED METHODS OF USE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2014-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140315886-A1 | QUINAZOLINES AS THERAPEUTIC COMPOUNDS AND RELATED METHODS OF USE | PPP2CA, PPP4C, PPP3CB | MAP4K2 568/4885ABCG2 1597/4885MEN1 4814/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.