Urea

Urea

SCHEMBL1618388

C=C.NC(N)=O.c1cnnnc1

nearest known ligand 0.35

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Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.35
LMNA P02545 1/20 0.35
OR51E2 Q9H255 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
P2RX7 Q99572 1/20 0.31
F7 P08709 1/20 0.30
F3 P13726 1/20 0.30
SARM1 Q6SZW1 1/20 0.30
SIRT2 Q8IXJ6 1/20 0.30
SIRT6 Q8N6T7 1/20 0.30
SIRT1 Q96EB6 1/20 0.30
SIRT3 Q9NTG7 1/20 0.30
SIRT5 Q9NXA8 1/20 0.30
SIRT4 Q9Y6E7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Urea SCHEMBL11744906 0.94 ALDH1A1 (0.35) ALDH1A1LMNAOR51E2TDP1P2RX7
Urea SCHEMBL10874658 0.94 ALDH1A1 (0.40) ALDH1A1LMNAOR51E2TDP1P2RX7
Carbamic Acid SCHEMBL2342697 0.85 ACHE (0.44) ALDH1A1LMNATDP1P2RX7F7
Carbamic Acid SCHEMBL2476276 0.85 ACHE (0.44) ALDH1A1LMNATDP1P2RX7F7
Acetamide SCHEMBL5605742 0.82 LMNA (0.47) ALDH1A1LMNATDP1P2RX7F7
Acrylamide SCHEMBL27945825 0.81 ALDH1A1 (0.55) ALDH1A1LMNA
Acrylamide SCHEMBL28677896 0.81 ALDH1A1 (0.55) ALDH1A1LMNA
Ethylene SCHEMBL27487223 0.80
SCHEMBL28124294 0.78 CRBN (0.38) LMNAP2RX7
Bicarbonate SCHEMBL9005252 0.78 CA1 (0.36) LMNAP2RX7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060137104-A1 Method of producing fabric ZHANG YU-GAO 2006-06-29 US claimed
EP-1492918-A4 METHOD OF PRODUCING FABRIC GUANGDONG ESQUEL KNITTERS CO L (CN) 2006-06-21 EP claimed
EP-1492918-A2 METHOD OF PRODUCING FABRIC Guangdong Esquel Kniiters Co., Ltd. (CN) 2005-01-05 EP claimed
WO-2003060222-A2 METHOD OF PRODUCING FABRIC GUANGDONG ESQUEL KNITTERS CO., LTD. (CN) 2003-07-24 WO claimed
US-20030135932-A1 Method of producing fabric GUANGDONG ESQUEL KNITTERS CO., LTD. (CN) 2003-07-24 US claimed
US-4478660-A FORMING LAMINATE OF CURABLE RESING AND CELLULOSE FILLER AND HEATING ALKOR GMBH KUNSTSTOFFVERKAUF (DE) 1984-10-23 US claimed
JP-4361668-A None JP disclosed
US-7922776-B2 Shrinkage inhibition; wrinkle resistance; contacting cellulose with enzyme; then overcoating with polymer ZHANG YU-GAO 2011-04-12 US disclosed
US-20060137104-A1 Method of producing fabric ZHANG YU-GAO 2006-06-29 US disclosed
EP-1492918-A4 METHOD OF PRODUCING FABRIC GUANGDONG ESQUEL KNITTERS CO L (CN) 2006-06-21 EP disclosed
EP-1492918-A2 METHOD OF PRODUCING FABRIC Guangdong Esquel Kniiters Co., Ltd. (CN) 2005-01-05 EP disclosed
WO-2003060222-A2 METHOD OF PRODUCING FABRIC GUANGDONG ESQUEL KNITTERS CO., LTD. (CN) 2003-07-24 WO disclosed
US-20030135932-A1 Method of producing fabric GUANGDONG ESQUEL KNITTERS CO., LTD. (CN) 2003-07-24 US disclosed
EP-0494371-B1 Adhesive-active polyester yarn BRIDGESTONE FIRESTONE INC (US) 1996-05-08 EP disclosed
JP-H04361668-A POLYESTER FIBER YARN HAVING EXCELLENT BONDING PROPERTY BRIDGESTONE CORP 1992-12-15 JP disclosed
EP-0494371-A1 Adhesive-active polyester yarn BRIDGESTONE/FIRESTONE, INC. (US) 1992-07-15 EP disclosed
US-5128054-A Aziridine containing finish overcoat BRIDGESTONE/FIRESTONE, INC. (US) 1992-07-07 US disclosed
US-4964884-A Flexible grinding tool and process for producing it Inorddeutsche Industrie Christianson & Co. (GmbH & Co.) (DE) 1990-10-23 US disclosed