SCHEMBL16185352

SCHEMBL16185352

Cc1ccc(-c2cccc3c2oc2c(C)cccc23)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA3 P0DMS8 2/20 0.50
MCL1 Q07820 1/20 0.40
ALOX5 P09917 1/20 0.40
MAOB P27338 3/20 0.38
TNKS O95271 2/20 0.38
PARP1 P09874 2/20 0.38
TNKS2 Q9H2K2 2/20 0.38
PARP2 Q9UGN5 1/20 0.38
COMT P21964 1/20 0.37
CSNK2A2 P19784 1/20 0.37
CSNK2B P67870 1/20 0.37
CSNK2A1 P68400 1/20 0.37
ADORA2A P29274 1/20 0.37
ADORA1 P30542 1/20 0.37
ENPP1 P22413 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP2A6 P11509 1/20 0.37
TP53 P04637 1/20 0.35
POLB P06746 1/20 0.35
MAPT P10636 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9917225 0.87 ADORA3 (0.49) ADORA3MCL1ALOX5MAOBCSNK2A2
SCHEMBL9917224 0.87 NPC1 (0.47) ADORA3ALOX5MAOBTNKSPARP1
SCHEMBL9917177 0.86 NPC1 (0.46) ADORA3ALOX5MAOBTNKSPARP1
SCHEMBL12799811 0.85 MCL1 (0.47) ADORA3MCL1ALOX5MAOBADORA2A
SCHEMBL12799833 0.84 ALOX5 (0.44) ADORA3MCL1ALOX5MAOBADORA2A
SCHEMBL8281469 0.83 RAB9A (0.53) CYP1A2TP53POLBMAPTNPC1
SCHEMBL16185353 0.83 TNKS (0.41) ADORA3MCL1ALOX5TNKSPARP1
SCHEMBL16185354 0.83 MCL1 (0.36) ADORA3MCL1ALOX5MAOBADORA2A
SCHEMBL16185355 0.83 S1PR1 (0.38) ADORA3MCL1ALOX5ADORA2AADORA1
SCHEMBL12799808 0.83 CA12 (0.43) ADORA3MCL1ALOX5MAOBADORA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140312340-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2014-10-23 US disclosed
US-20140312340-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2014-10-23 US disclosed