Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 5/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | EPHA2 | P29317 | 3/20 | 0.54 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.54 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | EFNA1 | P20827 | 1/20 | 0.54 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.54 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.54 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.54 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.54 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.54 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | CASP7 | P55210 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | BLM | P54132 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19064920 | 0.91 | GPBAR1 (0.54) | GPBAR1HSD17B10TDP1EPHA2AKR1B10 | |
| SCHEMBL7514775 | 0.89 | CYP2D6 (0.62) | GPBAR1HSD17B10TDP1EPHA2AKR1B10 | |
| SCHEMBL19064993 | 0.89 | GPBAR1 (0.53) | GPBAR1HSD17B10TDP1EPHA2AKR1B10 | |
| SCHEMBL9664069 | 0.89 | CYP2D6 (0.62) | GPBAR1HSD17B10TDP1EPHA2AKR1B10 | |
| SCHEMBL4751618 | 0.87 | GPBAR1 (0.74) | GPBAR1HSD17B10TDP1EPHA2AKR1B10 | |
| SCHEMBL9580113 | 0.87 | GPBAR1 (0.51) | GPBAR1HSD17B10TDP1EPHA2AKR1B10 | |
| SCHEMBL381612 | 0.87 | GPBAR1 (0.74) | GPBAR1HSD17B10TDP1EPHA2AKR1B10 | |
| SCHEMBL10906860 | 0.87 | GPBAR1 (0.74) | GPBAR1HSD17B10TDP1EPHA2AKR1B10 | |
| SCHEMBL7124131 | 0.86 | GPBAR1 (0.49) | GPBAR1HSD17B10TDP1EPHA2AKR1B10 | |
| SCHEMBL1492255 | 0.86 | GPBAR1 (0.49) | GPBAR1HSD17B10TDP1EPHA2AKR1B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110314166-A | Application of the Tauro ursodesoxy cholic acid in anti-hand-foot-and-mouth-disease poison and vesicular stomatitis virus drug | 武汉大学 | 2019-10-11 | — | — | CN | disclosed |
| CN-105891351-B | A kind of new Tauro ursodesoxy cholic acid content and the detection method in relation to substance | 中山百灵生物技术有限公司 | 2019-03-01 | — | — | CN | disclosed |
| CN-104382911-B | Application of the Tauro ursodesoxy cholic acid salt as active component in treatment Echinococcus Granulosus Cysts medicine is prepared | 姜玉峰 | 2017-09-15 | — | — | CN | disclosed |
| CN-106031731-A | New uses of tauroursodeoxycholic acid | 中国医学科学院基础医学研究所 | 2016-10-19 | — | — | CN | disclosed |
| CN-105699501-A | Method for detecting impurities in tauroursodeoxycholic acid through high performance liquid chromatograph | 成都欣捷高新技术开发有限公司 | 2016-06-22 | — | — | CN | disclosed |
| CN-103445007-B | Tauro ursodesoxy cholic acid is alleviating the application in chicken heat shock as feed addictive | SOUTH CHINA AGRICULTURAL UNIVERSITY (CN) | 2015-09-30 | — | — | CN | disclosed |
| US-9085602-B1 | Facial amphiphiles and methods of use | THE SCRIPPS RESEARCH INSTITUTE (US) | 2015-07-21 | — | — | US | disclosed |
| CN-104382911-A | Application of tauroursodeoxycholic acid salt used as active ingredient in preparation of drug for treating echinococcosis | JIANG YUFENG | 2015-03-04 | — | — | CN | disclosed |
| US-7922998-B2 | bombesin, derivatives and/or analogues capable of complexing metal ions, radionuclides or optical labels, for use in radiotherapy | BRACCO IMAGING S.P.A. (IT) | 2011-04-12 | — | — | US | disclosed |
| US-20060018830-A1 | Gastrin releasing peptide compounds | BRACCO IMAGING S.P.A. (IT) | 2006-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060018830-A1 | Gastrin releasing peptide compounds | GRPR, GIPR, CCKBR | GPBAR1 9/4885HSD17B10 4843/4885TDP1 4633/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.