Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 5/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
| ▸ | REN | P00797 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26695805 | 0.78 | ACE (0.45) | SPHK1ACEDPP4 | |
| SCHEMBL15305209 | 0.78 | ACE (0.54) | RAB9AACEACE2REN | |
| SCHEMBL17378268 | 0.77 | ACE (0.47) | RAB9AACEACE2REN | |
| SCHEMBL26724818 | 0.77 | ACE (0.47) | RAB9AACEACE2REN | |
| SCHEMBL19658296 | 0.77 | ACE (0.44) | SPHK1ACE | |
| SCHEMBL15305180 | 0.77 | DPP4 (0.50) | SPHK1DPP4 | |
| SCHEMBL21099985 | 0.74 | ACE (0.45) | ACE | |
| SCHEMBL20611455 | 0.73 | ACE (0.41) | SPHK1ACE | |
| SCHEMBL26724600 | 0.73 | ACE (0.41) | ACEACE2REN | |
| SCHEMBL15791258 | 0.73 | SMN1; SMN2 (0.49) | RAB9AACEACE2REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140315790-A1 | AMINOTHIAZOLES AND THEIR USES | BUSHELL SIMON (US) | 2014-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140315790-A1 | AMINOTHIAZOLES AND THEIR USES | ABAT, AADAT, GOT2 | RAB9A 3992/4885SPHK1 4547/4885ACE 29/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.