Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19658296 | 0.83 | ACE (0.44) | ACESPHK1 | |
| SCHEMBL20611525 | 0.77 | ACE (0.36) | ACE | |
| SCHEMBL26695805 | 0.75 | ACE (0.45) | ACESPHK1 | |
| SCHEMBL24590886 | 0.74 | ACE (0.35) | ACE | |
| SCHEMBL13272263 | 0.74 | ACE (0.45) | ACE | |
| SCHEMBL14979028 | 0.74 | ACE (0.45) | ACE | |
| SCHEMBL17378268 | 0.74 | ACE (0.47) | ACE | |
| SCHEMBL26724818 | 0.74 | ACE (0.47) | ACE | |
| SCHEMBL16185848 | 0.73 | RAB9A (0.41) | ACESPHK1 | |
| SCHEMBL24242099 | 0.73 | MVD (0.44) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3038640-B1 | SUBSTITUTED UREA DEPSIPEPTIDE ANALOGS AS ACTIVATORS OF THE CLPP ENDOPEPTIDASE | ST JUDE CHILDRENS RES HOSPITAL (US) | 2019-01-02 | — | — | EP | disclosed |