Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.46 |
| ▸ | CPT1A | P50416 | 3/20 | 0.43 |
| ▸ | CPT2 | P23786 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 4/20 | 0.42 |
| ▸ | HTR6 | P50406 | 5/20 | 0.41 |
| ▸ | PPARD | Q03181 | 3/20 | 0.40 |
| ▸ | PPARA | Q07869 | 3/20 | 0.40 |
| ▸ | CPT1B | Q92523 | 2/20 | 0.40 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.40 |
| ▸ | FABP4 | P15090 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11905795 | 0.86 | CPT1A (0.43) | SLC1A3SLC1A2SLC1A1CPT1ACPT2 | |
| SCHEMBL11905791 | 0.86 | CPT1A (0.43) | SLC1A3SLC1A2SLC1A1CPT1ACPT2 | |
| SCHEMBL10004725 | 0.77 | SLC1A3 (0.48) | SLC1A3SLC1A2SLC1A1CPT1ACPT2 | |
| SCHEMBL8652798 | 0.77 | CPT1A (0.63) | SLC1A3SLC1A2SLC1A1CPT1ACPT2 | |
| SCHEMBL7402844 | 0.76 | CPT1A (0.53) | SLC1A3SLC1A2SLC1A1CPT1ACPT2 | |
| SCHEMBL9372377 | 0.74 | CPT1A (0.54) | SLC1A3SLC1A2SLC1A1CPT1ACPT2 | |
| SCHEMBL30955477 | 0.74 | CPT1A (0.54) | SLC1A3SLC1A2SLC1A1CPT1ACPT2 | |
| SCHEMBL1898211 | 0.72 | HTR6 (0.56) | SLC1A3SLC1A2SLC1A1PPARGHTR6 | |
| SCHEMBL14722247 | 0.72 | HTR6 (0.48) | SLC1A3SLC1A2SLC1A1HTR6RAPGEF4 | |
| SCHEMBL17049296 | 0.70 | HTR6 (0.51) | SLC1A3SLC1A2SLC1A1PPARGHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9102692-B2 | Aminopyrazole derivative | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2015-08-11 | — | — | US | disclosed |
| US-9102692-B2 | Aminopyrazole derivative | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2015-08-11 | — | — | US | disclosed |
| US-20140315856-A1 | AMINOPYRAZOLE DERIVATIVE | F. HOFFMANN-LA ROCHE AG (CH) | 2014-10-23 | — | — | US | disclosed |
| US-20140315856-A1 | AMINOPYRAZOLE DERIVATIVE | F. HOFFMANN-LA ROCHE AG (CH) | 2014-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140315856-A1 | AMINOPYRAZOLE DERIVATIVE | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, IL4I1, CYP3A43 | SLC1A3 559/4885SLC1A2 1659/4885SLC1A1 648/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.