Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.51 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.50 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.50 |
| ▸ | RXRA | P19793 | 1/20 | 0.50 |
| ▸ | RXRB | P28702 | 1/20 | 0.50 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.50 |
| ▸ | IKBKB | O14920 | 1/20 | 0.49 |
| ▸ | DDT | P30046 | 1/20 | 0.49 |
| ▸ | DHODH | Q02127 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2213546 | 0.87 | KMO (0.73) | KMOPTGER1FOLH1NR1H4RXRA | |
| SCHEMBL30259065 | 0.87 | KMO (0.73) | KMOPTGER1FOLH1NR1H4RXRA | |
| SCHEMBL407806 | 0.86 | KMO (0.53) | KMOPTGER1FOLH1NR1H4RXRA | |
| SCHEMBL29629597 | 0.86 | KMO (0.53) | KMOPTGER1FOLH1NR1H4RXRA | |
| SCHEMBL3785593 | 0.86 | BAZ2B (0.52) | ALDH1A1HSD17B10DHODHPDK2 | |
| SCHEMBL1707626 | 0.85 | KMO (0.70) | KMOPTGER1FOLH1NR1H4RXRA | |
| SCHEMBL382724 | 0.85 | KMO (0.70) | KMOPTGER1FOLH1NR1H4RXRA | |
| SCHEMBL4671323 | 0.85 | KMO (0.51) | KMOPTGER1FOLH1NR1H4RXRA | |
| Hydrochloric Acid SCHEMBL4861328 | 0.85 | KMO (0.51) | KMOPTGER1FOLH1NR1H4RXRA | |
| Bromide SCHEMBL1706405 | 0.85 | KMO (0.51) | KMOPTGER1FOLH1NR1H4RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9085579-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2015-07-21 | — | — | US | disclosed |
| US-9085579-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2015-07-21 | — | — | US | disclosed |
| US-9085579-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2015-07-21 | — | — | US | disclosed |
| US-8735630-B2 | Transition-metal-catalyzed carbon-nitrogen and carbon-carbon bond-forming reactions | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2014-05-27 | — | — | US | disclosed |
| US-20130178632-A1 | Transition-Metal-Catalyzed Carbon-Nitrogen and Carbon-Carbon Bond-Forming Reactions | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2013-07-11 | — | — | US | disclosed |
| US-8420050-B2 | Gastrin releasing peptide compounds | BRACCO IMAGING S.P.A. (IT) | 2013-04-16 | — | — | US | disclosed |
| US-8378145-B2 | Transition-metal-catalyzed carbon-nitrogen and carbon-carbon bond-forming reactions | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2013-02-19 | — | — | US | disclosed |
| US-20110315933-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2011-12-29 | — | — | US | disclosed |
| US-20110315933-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2011-12-29 | — | — | US | disclosed |
| US-20110315933-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2011-12-29 | — | — | US | disclosed |
| US-20090287016-A1 | Transition-Metal-Catalyzed Carbon-Nitrogen and Carbon-Carbon Bond-Forming Reactions | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2009-11-19 | — | — | US | disclosed |
| US-7560596-B2 | Transition-metal-catalyzed carbon-nitrogen and carbon-carbon bond-forming reactions | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2009-07-14 | — | — | US | disclosed |
| US-20090175786-A1 | Gastrin Releasing Peptide Compounds | BRACCO IMAGING S.P.A. (IT) | 2009-07-09 | — | — | US | disclosed |
| US-20080008649-A1 | Gastrin Releasing Peptide Compounds | BRACCO IMAGING S.P.A. (IT) | 2008-01-10 | — | — | US | disclosed |
| EP-1833605-A2 | TRANSITION-METAL-CATALYZED CARBON-NITROGEN AND CARBON-CARBON BOND-FORMING REACTIONS | Massachusetts Institute of Technology (US) | 2007-09-19 | — | — | EP | disclosed |
| US-20060173186-A1 | Transition-metal-catalyzed carbon-nitrogen and carbon-carbon bond-forming reactions | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2006-08-03 | — | — | US | disclosed |
| WO-2006074315-A2 | TRANSITION-METAL-CATALYZED CARBON-NITROGEN AND CARBON-CARBON BOND-FORMING REACTIONS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2006-07-13 | — | — | WO | disclosed |
| US-20060018830-A1 | Gastrin releasing peptide compounds | BRACCO IMAGING S.P.A. (IT) | 2006-01-26 | — | — | US | disclosed |
| US-6034211-A | β-sheet nucleating peptidomimetics | KELLY JEFFERY W (US) | 2000-03-07 | — | — | US | disclosed |
| WO-1997046547-A1 | β-SHEET NUCLEATING PEPTIDOMIMETICS | THE TEXAS A & M UNIVERSITY SYSTEM (US) | 1997-12-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090287016-A1 | Transition-Metal-Catalyzed Carbon-Nitrogen and Carbon-Carbon Bond-Forming Reactions | NBAS, APEX1, CBR3 | KMO 94/4885ALDH1A1 1530/4885HSD17B10 4559/4885 |
| US-20060173186-A1 | Transition-metal-catalyzed carbon-nitrogen and carbon-carbon bond-forming reactions | NBAS, APEX1, CBR3 | KMO 94/4885ALDH1A1 1530/4885HSD17B10 4559/4885 |
| US-20090175786-A1 | Gastrin Releasing Peptide Compounds | GRPR, SSTR5, GIPR | KMO 3963/4885ALDH1A1 4399/4885HSD17B10 4647/4885 |
| US-20080008649-A1 | Gastrin Releasing Peptide Compounds | GRPR, SSTR5, GIPR | KMO 3963/4885ALDH1A1 4399/4885HSD17B10 4647/4885 |
| US-20060018830-A1 | Gastrin releasing peptide compounds | GRPR, GIPR, CCKBR | KMO 3618/4885ALDH1A1 4360/4885HSD17B10 4843/4885 |
| US-20130178632-A1 | Transition-Metal-Catalyzed Carbon-Nitrogen and Carbon-Carbon Bond-Forming Reactions | NBAS, APEX1, CBR3 | KMO 94/4885ALDH1A1 1530/4885HSD17B10 4559/4885 |
| US-20110315933-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | EPCAM, L1CAM, VCL | KMO 2916/4885ALDH1A1 208/4885HSD17B10 4011/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.