SCHEMBL16186451

SCHEMBL16186451

CC(C)(C)OC(=O)N1CCC(CCC(=O)C2CCC[C@@H](C(=O)ON3C(=O)CCC3=O)C2)CC1

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ FAAH O00519 1/20 0.42
▸ DDB1 Q16531 1/20 0.41
▸ CRBN Q96SW2 1/20 0.41
▸ HPGD P15428 1/20 0.40
▸ GPR119 Q8TDV5 10/20 0.39
▸ KDM4E B2RXH2 1/20 0.39
▸ PKM P14618 1/20 0.39
▸ MEN1 O00255 1/20 0.38
▸ ALDH1A1 P00352 1/20 0.38
▸ MAPT P10636 1/20 0.38
▸ KMT2A Q03164 1/20 0.38
▸ NPC1 O15118 1/20 0.37
▸ RAB9A P51151 1/20 0.37
▸ RECQL P46063 1/20 0.37
▸ EPHX1 P07099 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14698321 0.83 HPGD (0.45) FAAHDDB1CRBNHPGDGPR119
SCHEMBL5494939 0.81 HPGD (0.52) HPGDGPR119KDM4EMAPTKMT2A
SCHEMBL17469340 0.77 HPGD (0.50) HPGDGPR119KDM4EMEN1ALDH1A1
SCHEMBL12071961 0.77 HPGD (0.50) HPGDGPR119KDM4EMEN1ALDH1A1
SCHEMBL17776135 0.76 NR1H2 (0.47) DDB1CRBNHPGDKDM4EMEN1
SCHEMBL9014148 0.76 KDM4E (0.46) FAAHDDB1CRBNHPGDGPR119
SCHEMBL19658183 0.74 CHRM2 (0.36) KMT2A
SCHEMBL18751701 0.74 CHRM2 (0.36) KMT2A
SCHEMBL19658172 0.74 CHRM2 (0.36) KMT2A
SCHEMBL18275003 0.74 HPGD (0.43) DDB1CRBNHPGDKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140314669-A1 COMPOUNDS FOR BINDING TO THE PLATELET SPECIFIC GLYCOPROTEIN IIB/IIIA AND THEIR USE FOR IMAGING OF THROMBI PIRAMAL IMAGING SA (CH) 2014-10-23 — — US disclosed
US-20140314669-A1 COMPOUNDS FOR BINDING TO THE PLATELET SPECIFIC GLYCOPROTEIN IIB/IIIA AND THEIR USE FOR IMAGING OF THROMBI PIRAMAL IMAGING SA (CH) 2014-10-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140314669-A1 COMPOUNDS FOR BINDING TO THE PLATELET SPECIFIC GLYCOPROTEIN IIB/IIIA AND THEIR USE FOR IMAGING OF THROMBI F13B, FGB, SELPLG FAAH 3297/4885DDB1 2303/4885CRBN 1459/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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