SCHEMBL16188178

SCHEMBL16188178

CO[C@@H]1OC(C(=O)O)[C@@H](O[C@@H]2OC(C(=O)O)[C@@H](O)[C@H](O)C2O)[C@H](O)C1O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ F10 P00742 2/20 0.40
▸ FGF2 P09038 1/20 0.39
▸ BDNF P23560 3/20 0.38
▸ PTN P21246 2/20 0.38
▸ MDK P21741 2/20 0.38
▸ AKT1 P31749 1/20 0.38
▸ M6PR P20645 2/20 0.37
▸ LMNA P02545 1/20 0.36
▸ FGF1 P05230 1/20 0.36
▸ KDM4E B2RXH2 1/20 0.36
▸ ALDH1A1 P00352 1/20 0.36
▸ GLA P06280 1/20 0.36
▸ HPGD P15428 1/20 0.36
▸ MAPK1 P28482 1/20 0.36
▸ HSD17B10 Q99714 1/20 0.36
▸ IDUA P35475 1/20 0.36
▸ CXCL10 P02778 1/20 0.36
▸ CXCL8 P10145 1/20 0.36
▸ CCL2 P13500 1/20 0.36
▸ CCL5 P13501 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21385960 1.00 F10 (0.40) F10FGF2BDNFPTNMDK
SCHEMBL12384884 0.92 F10 (0.43) F10BDNFPTNMDKM6PR
SCHEMBL22139521 0.92 F10 (0.43) F10BDNFPTNMDKM6PR
SCHEMBL20363547 0.92 F10 (0.43) F10BDNFPTNMDKM6PR
SCHEMBL20363815 0.92 F10 (0.43) F10BDNFPTNMDKM6PR
SCHEMBL12878540 0.92 F10 (0.43) F10BDNFPTNMDKM6PR
SCHEMBL12458629 0.92 F10 (0.43) F10BDNFPTNMDKM6PR
SCHEMBL12755226 0.92 F10 (0.43) F10BDNFPTNMDKM6PR
SCHEMBL20370858 0.92 F10 (0.43) F10BDNFPTNMDKM6PR
SCHEMBL18309852 0.92 F10 (0.43) F10BDNFPTNMDKM6PR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140314722-A1 MATRICES COMPRISING A MODIFIED POLYSACCHARIDE ALBERT-LUDWIGS UNIVERSITÄT FREIBURG (DE) 2014-10-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140314722-A1 MATRICES COMPRISING A MODIFIED POLYSACCHARIDE FUT5, FUT6, CSGALNACT1 F10 162/4885FGF2 268/4885BDNF 2039/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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