SCHEMBL12458629

SCHEMBL12458629

CO[C@@H]1O[C@@H](C(=O)O)[C@@H](O[C@@H]2OC(C(=O)O)[C@@H](O[C@@H]3O[C@@H](C(=O)O)[C@@H](O[C@@H]4OC(C(=O)O)[C@@H](OC)[C@@H](O)C4O)C(O)C3O)[C@H](O)C2O)C(O)C1O

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ F10 P00742 6/20 0.43
▸ CXCL10 P02778 1/20 0.39
▸ CXCL8 P10145 1/20 0.39
▸ CCL2 P13500 1/20 0.39
▸ CCL5 P13501 1/20 0.39
▸ CXCL12 P48061 1/20 0.39
▸ M6PR P20645 2/20 0.38
▸ SERPINC1 P01008 2/20 0.37
▸ FGF1 P05230 2/20 0.36
▸ LGALS8 O00214 2/20 0.35
▸ BDNF P23560 3/20 0.35
▸ PTN P21246 2/20 0.35
▸ MDK P21741 2/20 0.35
▸ G6PD P11413 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12901064 1.00 F10 (0.43) F10CXCL10CXCL8CCL2CCL5
SCHEMBL20363815 1.00 F10 (0.43) F10CXCL10CXCL8CCL2CCL5
SCHEMBL14030121 1.00 F10 (0.43) F10CXCL10CXCL8CCL2CCL5
SCHEMBL20370858 1.00 F10 (0.43) F10CXCL10CXCL8CCL2CCL5
SCHEMBL12755226 1.00 F10 (0.43) F10CXCL10CXCL8CCL2CCL5
SCHEMBL20363547 1.00 F10 (0.43) F10CXCL10CXCL8CCL2CCL5
SCHEMBL12878540 1.00 F10 (0.43) F10CXCL10CXCL8CCL2CCL5
SCHEMBL12384884 1.00 F10 (0.43) F10CXCL10CXCL8CCL2CCL5
SCHEMBL22139521 1.00 F10 (0.43) F10CXCL10CXCL8CCL2CCL5
SCHEMBL18309852 1.00 F10 (0.43) F10CXCL10CXCL8CCL2CCL5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9358203-B2 Multi-purpose cosmetic compositions MARY KAY INC. (US) 2016-06-07 — — US disclosed
US-20160136086-A1 COSMETIC FORMULATION MARY KAY INC. 2016-05-19 — — US disclosed
US-9320702-B2 Multi-Purpose cosmetic compositions MARY KAY INC. (US) 2016-04-26 — — US disclosed
US-20140328958-A1 Multi-Purpose Cosmetic Compositions ALLUSTRA TECHNOLOGIES LLC 2014-11-06 — — US disclosed
US-8877259-B2 Cosmetic formulation MARY KAY INC. (US) 2014-11-04 — — US disclosed
US-8759282-B2 Water-soluble films comprising low-viscosity alginates UPPSALAGRUPPEN MEDICAL AB (SE) 2014-06-24 — — US disclosed
US-20130209504-A1 COSMETIC FORMULATION MARY KAY INC. (US) 2013-08-15 — — US disclosed
US-20120237540-A1 Multi-Purpose Cosmetic Compositions MARY KAY INC. (US) 2012-09-20 — — US disclosed
US-20100087550-A1 Formulations with a Tertiary Amine Oxide BAUSCH & LOMB MEXICO, S.A. DE C.V. (MX) 2010-04-08 — — US disclosed
US-20090221489-A1 Water-Soluable Films Comprising Low-Viscosity Alginates EXCELLENS TECH. PRODUCTS APS (DK) 2009-09-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160136086-A1 COSMETIC FORMULATION CUTA, SYMPK, SGMS1 F10 2528/4885CXCL10 1881/4885CXCL8 1269/4885
US-20120237540-A1 Multi-Purpose Cosmetic Compositions BMI1, CUTA, LPO F10 4194/4885CXCL10 2214/4885CXCL8 1909/4885
US-20140328958-A1 Multi-Purpose Cosmetic Compositions BMI1, CUTA, LPO F10 4194/4885CXCL10 2214/4885CXCL8 1909/4885
US-20130209504-A1 COSMETIC FORMULATION SGMS1, SGMS2, CHKB F10 2635/4885CXCL10 1520/4885CXCL8 1938/4885
US-20100087550-A1 Formulations with a Tertiary Amine Oxide C1S, C1R, C5 F10 427/4885CXCL10 2431/4885CXCL8 3533/4885
US-20090221489-A1 Water-Soluable Films Comprising Low-Viscosity Alginates ALG1, SMARCA2, MUC1 F10 203/4885CXCL10 4608/4885CXCL8 3308/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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