SCHEMBL16189596

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16189054	0.95	L3MBTL1 (0.39)	L3MBTL1CYP2A6TNFCHEK1MAOA
	SCHEMBL21034053	0.91	CYP2A6 (0.48)	L3MBTL1CYP2A6TNFCHEK1MAOA
	SCHEMBL17655896	0.82	ALDH1A1 (0.48)	L3MBTL1TNFLMNAMAPK9CLK4
	SCHEMBL16189301	0.81	CYP2A6 (0.46)	L3MBTL1CYP2A6TNFMAOALMNA
	SCHEMBL16716533	0.81	ALDH1A1 (0.50)	L3MBTL1TNFLMNAMAPK9CLK4
	SCHEMBL16716596	0.80	L3MBTL1 (0.50)	L3MBTL1LMNAMEN1ALDH1A1MAPT
	SCHEMBL16189413	0.80	MKNK1 (0.55)	L3MBTL1LMNAMKNK1MKNK2MEN1
	SCHEMBL27455783	0.79	ALDH1A1 (0.45)	L3MBTL1TNFLMNAKCNH2KCNA5
	SCHEMBL17829272	0.78	SMN1; SMN2 (0.50)	L3MBTL1TNFLMNAKCNH2KCNA5
	SCHEMBL16189062	0.78	MKNK1 (0.57)	L3MBTL1LMNAMKNK1MKNK2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.